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4 results on '"Barreca, Antonella"'

1. Clinicopathologic predictors of renal outcomes in light chain cast nephropathy: a multicenter retrospective study

Author

Royal, Virginie, Leung, Nelson, Troyanov, Stéphan, Nasr, Samih H., Écotière, Laure, LeBlanc, Richard, Adam, Benjamin A., Angioi, Andrea, Alexander, Mariam P., Asunis, Anna Maria, Barreca, Antonella, Bianco, Paola, Cohen, Camille, Drosou, Maria E., Fatima, Huma, Fenoglio, Roberta, Gougeon, François, Goujon, Jean-Michel, Herrera, Guillermo A., Knebelmann, Bertrand, Lepori, Nicola, Maletta, Francesca, Manso, Rita, Motwani, Shveta S., Pani, Antonello, Rabant, Marion, Rennke, Helmut G., Rocatello, Dario, Rosenblum, Frida, Sanders, Paul W., Santos, Afonso, Soto, Karina, Sis, Banu, Touchard, Guy, Venner, Christopher P., and Bridoux, Frank

Published
2020
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2. Identification of a new subclass of ALK-negative ALCL expressing aberrant levels of ERBB4 transcripts

Author

Scarfò, Irene, Pellegrino, Elisa, Mereu, Elisabetta, Kwee, Ivo, Agnelli, Luca, Bergaggio, Elisa, Garaffo, Giulia, Vitale, Nicoletta, Caputo, Manuel, Machiorlatti, Rodolfo, Circosta, Paola, Abate, Francesco, Barreca, Antonella, Novero, Domenico, Mathew, Susan, Rinaldi, Andrea, Tiacci, Enrico, Serra, Sara, Deaglio, Silvia, Neri, Antonino, Falini, Brunangelo, Rabadan, Raul, Bertoni, Francesco, Inghirami, Giorgio, and Piva, Roberto

Published
2016
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3. microRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma

Author

Liu, Cuiling, Iqbal, Javeed, Teruya-Feldstein, Julie, Shen, Yulei, Dabrowska, Magdalena Julia, Dybkaer, Karen, Lim, Megan S., Piva, Roberto, Barreca, Antonella, Pellegrino, Elisa, Spaccarotella, Elisa, Lachel, Cynthia M., Kucuk, Can, Jiang, Chun-Sun, Hu, Xiaozhou, Bhagavathi, Sharathkumar, Greiner, Timothy C., Weisenburger, Dennis D., Aoun, Patricia, Perkins, Sherrie L., McKeithan, Timothy W., Inghirami, Giorgio, and Chan, Wing C.

Published
2013
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4. microRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphoma.

Author

Cuiling Liu, Javeed Iqbal, Julie Teruya-Feldstein, Shen, Yulei, Dabrowska, Magdalena Julia, Dybkaer, Karen, Lim, Megan S., Piva, Roberto, Barreca, Antonella, Pellegrino, Elisa, Spaccarotella, Elisa, Lachel, Cynthia M., Kucuk, Can, Chun-Sun Jiang, Xiaozhou Hu, Sharathkumar Bhagavathi, Greiner, Timothy C., Weisenburger, Dennis D., Aoun, Patricia, and Perkins, Sherrie L.

Subjects
*MICRORNA, *T-cell lymphoma, *ANAPLASTIC lymphoma kinase, *IN vitro studies, *ONCOGENIC proteins
Abstract

Anaplastic large-cell lymphomas (ALCLs) encompass at least 2 systemic diseases distinguished by the presence or absence of anaplastic lymphoma kinase (ALK) expression. We performed genome-wide microRNA (miRNA) profiling on 33 ALK-positive (ALK[+]) ALCLs, 25 ALK-negative (ALK[-]) ALCLs, 9 angioimmunoblastic T-cell lymphomas, 11 peripheral T-cell lymphomas not otherwise specified (PTCLNOS), and normal T cells, and demonstrated that ALCLs express many of the miRNAs that are highly expressed in normal T ceils with the prominent exception of miR-146a. Unsupervised hierarchical clustering demonstrated distinct clustering of ALCL, PTCL-NOS, and the AITL subtype of PTCL. Cases of ALK(+) ALCL and ALK(-) ALCL were interspersed in unsupervised analysis, suggesting a close relationship at the molecular level. We identified an miRNA signature of 7 miRNAs (5 upregulated: miR-512-3p, miR-886-5p, miR-886-3p, miR-708, miR-135b; 2 downregulated: miR-146a, miR-155) significantly associated with ALK(+) ALCL cases. In addition, we derived an 11 -miRNA signature (4 upregulated: miR-210, miR-197, miR-191, miR-512-3p; 7 downregulated: miR-451, miR-146a, miR-22, miR-455-3p, miR-455-5p, miR-143, miR-494) that differentiates ALK(-) ALCL from other PTCLs. Our in vitro studies identified a set of 32 miRNAs associated with ALK expression. Of these, the miR-17-92 cluster and its paralogues were also highly expressed in ALK(+) ALCL and may represent important downstream effectors of the ALK oncogenic pathway. [ABSTRACT FROM AUTHOR]

Published
2013
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