48 results on '"Beer, Philip A"'
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2. A topological view of human CD34+ cell state trajectories from integrated single-cell output and proteomic data
3. Distinct signaling programs control human hematopoietic stem cell survival and proliferation
4. Disruption of IKAROS activity in primitive chronic-phase CML cells mimics myeloid disease progression
5. CTPS1 Is a Novel Therapeutic Target in Multiple Myeloma That Synergizes with Inhibition of ATR, CHEK1 or WEE1
6. STP938, a Selective CTPS1 Inhibitor, Shows Single Agent Activity and Synergy with BCL2 Inhibition in Preclinical Models of Mantle Cell Lymphoma
7. A Phase 1/2 Study of STP938, a First in Class Inhibitor of CTP Synthase 1, in Patients with Relapsed/Refractory B or T Cell Lymphoma
8. Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice
9. Enhanced normal short-term human myelopoiesis in mice engineered to express human-specific myeloid growth factors
10. How I treat essential thrombocythemia
11. JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F–positive essential thrombocythemia
12. The JAK2 46/1 haplotype predisposes to MPL-mutated myeloproliferative neoplasms
13. Two routes to leukemic transformation after a JAK2 mutation–positive myeloproliferative neoplasm
14. MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort
15. Targeted sequencing in DLBCL, molecular subtypes, and outcomes: a Haematological Malignancy Research Network report
16. NUP98-HOXA9-Initiates Molecular and Biologic Features of Disease Progression in a Humanized Model of CML
17. Results of a First in Human, Dose Ascending, Phase I Study Examining the Safety and Tolerability of KA2237, an Oral PI3K p110β/δ Inhibitor in Patients with Relapsed/Refractory (R/R) B-Cell Lymphoma
18. Growth Factor-Dependent Activation of a MYC-Induced Latent AML Program in Human Hematopoietic Cells
19. Modeling de novo leukemogenesis from human cord blood with MN1 and NUP98HOXD13
20. Enhanced and Accelerated Repopulation of Mutant C-Kit Immunodeficient Mice By Transplants of Primary Chronic and Acute Myeloid Leukemic Human Cells
21. A topological view of human CD34+cell state trajectories from integrated single-cell output and proteomic data
22. Correlation of blood counts with vascular complications in essential thrombocythemia: analysis of the prospective PT1 cohort
23. Longterm Multilineage Human Hematopoietic Repopulation of Untreated KIT-Mutant Immunodeficient Mice
24. Effects of the JAK2 mutation on the hematopoietic stem and progenitor compartment in human myeloproliferative neoplasms
25. Disruption Of Ikaros In Patients’ Chronic Phase CML Cells Induces The Features Of Accelerated Phase Disease
26. Novel exon 12 mutations in the HIF2A gene associated with erythrocytosis
27. Longterm Serial Transplantability of BCR-ABL+ Chronic Phase CML Cells Is Predicted by a 6-Week LTC-IC Assay.
28. Time Course Studies of the Progeny of Barcoded CD34+ Human Cord Blood Cells Generated in Transplanted NOD/SCID-IL2Rγ−/− Mice Unveil the Clonal Dynamics of Short Term, Intermediate Term and Long Term Repopulating Cells
29. Distinct Human Cell Populations Produce Rapidly Detectable Levels of Neutrophils and Platelets in NOD/SCID-IL-2Receptor Gamma Chain Null Mice Transgenically Engineered to Produce Human Myeloid Growth Factors
30. Increased basal intracellular signaling patterns do not correlate with JAK2 genotype in human myeloproliferative neoplasms
31. Response: essential thrombocythemia: seeing the wood for the trees
32. Independently acquired biallelic JAK2 mutations are present in a minority of patients with essential thrombocythemia
33. A novel erythrocytosis-associated PHD2 mutation suggests the location of a HIF binding groove
34. The JAK2 46/1 Haplotype Predisposes to Myeloproliferative Neoplasms Characterized by Diverse Mutations.
35. HIF-2alpha Associated Familial Erythrocytosis Supports the PHD2-HIF- 2alpha-VHL Axis as the Major Regulator of Erythropoietin Production
36. Clinical Significance of MPL Mutations in Essential Thrombocythemia: Analysis of the PT-1 Cohort.
37. Increased basal intracellular signaling patterns do not correlate with JAK2genotype in human myeloproliferative neoplasms
38. The JAK246/1 haplotype predisposes to MPL-mutated myeloproliferative neoplasms
39. Two routes to leukemic transformation after a JAK2mutation–positive myeloproliferative neoplasm
40. MPLmutations in myeloproliferative disorders: analysis of the PT-1 cohort
41. Mutation of JAK2in the myeloproliferative disorders: timing, clonality studies, cytogenetic associations, and role in leukemic transformation
42. Mutation of JAK2 in the myeloproliferative disorders: timing, clonality studies, cytogenetic associations, and role in leukemic transformation
43. Novel exon 12 mutations in the HIF2Agene associated with erythrocytosis
44. Independently acquired biallelic JAK2mutations are present in a minority of patients with essential thrombocythemia
45. Enhanced and Accelerated Repopulation of Mutant C-KitImmunodeficient Mice By Transplants of Primary Chronic and Acute Myeloid Leukemic Human Cells
46. Time Course Studies of the Progeny of Barcoded CD34+Human Cord Blood Cells Generated in Transplanted NOD/SCID-IL2Rγ−/−Mice Unveil the Clonal Dynamics of Short Term, Intermediate Term and Long Term Repopulating Cells
47. Brief report: Correlation of blood counts with vascular complications in essential thrombocythemia: analysis of the prospective PT1 cohort.
48. Analysis of the clonal growth and differentiation dynamics of primitive barcoded human cord blood cells in NSG mice.
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