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Your search keyword '"Bröckelmann, Paul J."' showing total 16 results
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16 results on '"Bröckelmann, Paul J."'

1. Tumor and microenvironment response but no cytotoxic T-cell activation in classic Hodgkin lymphoma treated with anti-PD1

Author

Reinke, Sarah, Bröckelmann, Paul J., Iaccarino, Ingram, Garcia-Marquez, Maria, Borchmann, Sven, Jochims, Franziska, Kotrova, Michaela, Pal, Karol, Brüggemann, Monika, Hartmann, Elena, Sasse, Stephanie, Kobe, Carsten, Mathas, Stephan, Soekler, Martin, Keller, Ulrich, Bormann, Matthias, Zimmermann, Andreas, Richter, Julia, Fuchs, Michael, von Tresckow, Bastian, Borchmann, Peter, Schlößer, Hans, von Bergwelt-Baildon, Michael, Rosenwald, Andreas, Engert, Andreas, and Klapper, Wolfram

Published
2020
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4. Nivolumab and AVD in Early-Stage Unfavorable Hodgkin Lymphoma: Follow-up Analysis of the Randomized GHSG Phase II Nivahl Trial

Author

Bröckelmann, Paul J, primary, Bühnen, Ina, additional, Meissner, Julia, additional, Trautmann-Grill, Karolin, additional, Herhaus, Peter, additional, Halbsguth, Teresa V, additional, Schaub, Valdete, additional, Kerkhoff, Andrea, additional, Mathas, Stephan, additional, Bormann, Matthias, additional, Dickhut, Andreas, additional, Kaul, Helen, additional, Fuchs, Michael, additional, Kobe, Carsten, additional, Baues, Christian, additional, Borchmann, Peter, additional, Engert, Andreas, additional, and von Tresckow, Bastian, additional

Published
2022
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5. Outcomes of Anti-PD1 Treatment for Relapsed/Refractory Hodgkin Lymphoma: A German Hodgkin Study Group (GHSG) Multi-Center Real-World Analysis

Author

Momotow, Jesko, primary, Bühnen, Ina, additional, Trautmann-Grill, Karolin, additional, Kobbe, Guido, additional, Wilhelm, Martin, additional, Heinrich, Bernhard, additional, Gaska, Tobias, additional, Forstbauer, Helmut, additional, Schmidt, Burkhard, additional, Hüttmann, Andreas, additional, Heil, Gerhard, additional, Kraemer, Doris M., additional, Krüger, William Hermann, additional, Zeremski, Vanja, additional, Grobe, Norbert, additional, Jentsch-Ulrich, Kathleen, additional, Fuchs, Michael, additional, von Tresckow, Bastian, additional, Borchmann, Peter, additional, Engert, Andreas, additional, and Bröckelmann, Paul J, additional

Published
2021
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6. Impact of Timing and Precision of Histopathological Diagnosis on Outcomes of Patients with Burkitt and High-Grade B-Cell Lymphoma

Author

Heger, Jan-Michel, primary, Graef, Claus Moritz, additional, Falderbaum, Philipp, additional, Gödel, Philipp, additional, Balke-Want, Hyatt, additional, Simon, Florian, additional, Sieg, Noëlle, additional, Naendrup, Jan-Hendrik, additional, Neumann, Marie Anne-Catherine, additional, Gillessen, Sarah, additional, Bröckelmann, Paul J, additional, Eichenauer, Dennis A., additional, Borchmann, Peter, additional, and Von Tresckow, Bastian, additional

Published
2021
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7. Efficacy and Safety of Nivolumab and AVD in Early-Stage Unfavorable Hodgkin Lymphoma: Extended Follow-up from the GHSG Phase II Nivahl Trial

Author

Bröckelmann, Paul J, primary, Goergen, Helen, additional, Keller, Ulrich, additional, Meissner, Julia, additional, Trautmann, Karolin, additional, Halbsguth, Teresa V, additional, Sasse, Stephanie, additional, Sökler, Martin, additional, Kerkhoff, Andrea, additional, Mathas, Stephan, additional, Hüttmann, Andreas, additional, Bormann, Matthias, additional, Zimmermann, Andreas, additional, Fuchs, Michael, additional, von Tresckow, Bastian, additional, Baues, Christian, additional, Rosenwald, Andreas, additional, Klapper, Wolfram, additional, Kobe, Carsten, additional, Borchmann, Peter, additional, and Engert, Andreas, additional

Published
2020
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8. Nivolumab and AVD for Early-Stage Unfavorable Hodgkin Lymphoma (NIVAHL)

Author

Bröckelmann, Paul J, primary, Goergen, Helen, primary, Keller, Ulrich, primary, Meissner, Julia, primary, Ordemann, Rainer, primary, Halbsguth, Teresa V, primary, Sasse, Stephanie, primary, Sökler, Martin, primary, Kerkhoff, Andrea, primary, Mathas, Stephan, primary, Hüttmann, Andreas, primary, Bormann, Matthias, primary, Zimmermann, Andreas, primary, Fuchs, Michael, primary, von Tresckow, Bastian, primary, Baues, Christian, primary, Rosenwald, Andreas, primary, Klapper, Wolfram, primary, Kobe, Carsten, primary, Borchmann, Peter, primary, and Engert, Andreas, primary

Published
2019
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9. Abscopal Effect of Radiotherapy and Nivolumab in Relapsed or Refractory Hodgkin Lymphoma (AERN): An International Multicenter Single-Arm Two-Stage Phase II GHSG Trial

Author

Bröckelmann, Paul J, primary, Plütschow, Annette, additional, Greil, Richard, additional, Zijlstra, Josée M, additional, Illidge, Timothy, additional, Fosså, Alexander, additional, Meissner, Julia, additional, Zimmermann, Andreas, additional, Mathas, Stephan, additional, Thol, Felicitas, additional, Fuchs, Michael, additional, Engert, Andreas, additional, and Baues, Christian, additional

Published
2019
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10. Metabolic Tumor Volume for Early Response Assessment in Early-Stage Unfavorable Hodgkin Lymphoma Treated with Nivolumab in the GHSG Nivahl Phase II Trial

Author

Voltin, Conrad-Amadeus, primary, Mettler, Jasmin, additional, Mueller, Horst, additional, Fuchs, Michael, additional, Baues, Christian, additional, Dietlein, Markus, additional, Engert, Andreas, additional, Borchmann, Peter, additional, Kobe, Carsten, additional, and Bröckelmann, Paul J, additional

Published
2019
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13. Fertility and Gonadal Function after First-Line Treatment with Nivolumab-AVD in Hodgkin Lymphoma Patients: An Analysis from the Phase II GHSG Nivahl Trial

Author

Bröckelmann, Paul J, Bühnen, Ina, Herhaus, Peter, Meissner, Julia, Trautmann-Grill, Karolin, Müller, Horst, Fuchs, Michael, von Tresckow, Bastian, Borchmann, Peter, Engert, Andreas, and Behringer, Karolin

Abstract

Background: First-line treatment of patients with classical Hodgkin lymphoma (HL) with anti-PD1 antibodies in combination with AVD chemotherapy is highly effective across risk-groups. Based on encouraging phase II and ongoing phase III trials, anti-PD1 based first-line treatment may hence soon become a first-line treatment option. To date, no data on fertility and gonadal function after anti-PD1 based first-line HL treatment is available. Herein, we present data on pregnancies and gonadal function in patients treated within the randomized GHSG phase II NIVAHL trial.

Published
2023
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14. Correlation between Progression-Free Survival and Overall Survival in Patients with Relapsed Hodgkin Lymphoma: An Analysis of Individual Patient Data from Randomized GHSG Trials

Author

Bröckelmann, Paul J, Müller, Horst, Gillessen, Sarah, Jacob, Anne Sophie, Momotow, Jesko, Damaschin, Carla, Ferdinandus, Justin, Yang, Xiaoqin, Fuchs, Michael, Kobe, Carsten, Eich, Hans Theodor, Engert, Andreas, Borchmann, Peter, and von Tresckow, Bastian

Abstract

Background: Progression-free survival (PFS) and overall survival (OS) are predominant measures of treatment efficacy in Hodgkin lymphoma (HL). Despite preference for OS from many regulatory authorities, PFS is most relevant to patients and frequently serves as primary endpoint in clinical trials. Recently we found a strong correlation between treatment effects on PFS and OS in the first-line setting (Bröckelmann PJ et al. EHA23/ICML23). However, their relationship in the relapsed setting remains unclear. We aimed to evaluate the correlation of PFS with OS after treatment of relapsed HL.

Published
2023
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16. Clinical Characteristics and Outcomes of Patients with Hodgkin Lymphoma with Central Nervous System Involvement: An International Multicenter Collaboration

Author

Cheah, Chan Yoon, Broeckelmann, Paul J, Moskowitz, Alison J, Engert, Andreas, Jerkeman, Mats, El-Galaly, Tarec Christoffer, Vose, Julie, Villa, Diego, Connors, Joseph M., Feldman, Tatyana, Chihara, Dai, Pinnix, Chelsea C, Milgrom, Sarah A, Dabaja, Bouthaina S., Oki, Yasuhiro, and Fanale, Michelle A.

Published
2015
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