193 results on '"Laurà, M"'
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2. Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles
3. A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels
4. Fetal factors disrupt placental and maternal iron homeostasis in murine β-thalassemia
5. The neurotransmitter receptor Gabbr1 regulates proliferation and function of hematopoietic stem and progenitor cells
6. Improving CLL Vγ9Vδ2-T–cell fitness for cellular therapy by ex vivo activation and ibrutinib
7. Phase 1/2 study of lenalidomide combined with low-dose cyclophosphamide and prednisone in lenalidomide-refractory multiple myeloma
8. Targeting of the bone marrow microenvironment improves outcome in a murine model of myelodysplastic syndrome
9. The hematopoietic stem cell niche in homeostasis and disease
10. Randomized phase 2 study of GMI-1070 in SCD: reduction in time to resolution of vaso-occlusive events and decreased opioid use
11. Distinct roles for hepcidin and interleukin-6 in the recovery from anemia in mice injected with heat-killed Brucella abortus
12. Mutant IDH1 promotes leukemogenesis in vivo and can be specifically targeted in human AML
13. Ovariectomy expands murine short-term hemopoietic stem cell function through T cell expressed CD40L and Wnt10B
14. Megakaryocytes assemble podosomes that degrade matrix and protrude through basement membrane
15. Umbrella Trial in Myeloid Malignancies: The Myelomatch National Clinical Trials Network Precision Medicine Initiative
16. Therapeutic Modulation of the Marrow Microenvironment in MDS: A Phase I Trial of Abaloparatide and Bevacizumab
17. PTH expands short-term murine hemopoietic stem cells through T cells
18. Osteoblastic N-cadherin is not required for microenvironmental support and regulation of hematopoietic stem and progenitor cells
19. The miR-17-92 cluster expands multipotent hematopoietic progenitors whereas imbalanced expression of its individual oncogenic miRNAs promotes leukemia in mice
20. Osteoblastic expansion induced by parathyroid hormone receptor signaling in murine osteocytes is not sufficient to increase hematopoietic stem cells
21. Functional inhibition of osteoblastic cells in an in vivo mouse model of myeloid leukemia
22. Outcome of AL amyloidosis after high-dose melphalan and autologous stem cell transplantation: long-term results in a series of 421 patients
23. Prothrombin activation on the activated platelet surface optimizes expression of procoagulant activity
24. The inositol phosphatase SHIP-1 is negatively regulated by Fli-1 and its loss accelerates leukemogenesis
25. In vivo prostaglandin E2 treatment alters the bone marrow microenvironment and preferentially expands short-term hematopoietic stem cells
26. Modeling the functional heterogeneity of leukemia stem cells: role of STAT5 in leukemia stem cell self-renewal
27. Enrichment of Sca1+ hematopoietic progenitors in polycythemic mice inhibits leukemogenesis
28. SHIP prevents lipopolysaccharide from triggering an antiviral response in mice
29. Translatome Proteomics Identifies Autophagy As a Resistance Mechanism to on-Target FLT3 Inhibitors in Acute Myeloid Leukemia
30. Identification of genetic polymorphisms associated with risk for pulmonary hypertension in sickle cell disease
31. Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia
32. Primary Analysis of Spartan: A Phase 2 Trial to Assess the Efficacy and Safety of Crizanlizumab in Patients with Sickle Cell Disease Related Priapism
33. Immune-Effector-Cell-Associated-Neurotoxicity-Syndrome (ICANS) Pathophysiology Is Mediated By Microglia TGF-β-Activated Kinase-1 Signaling
34. Real-World Experience of Individuals with Sickle Cell Disease Treated with Voxelotor: Initial Report from the Multicenter, Prospective Prospect Study
35. Assessing Pain Severity in Sickle Cell Disease Using Animations and a Graphical Body Image
36. A Randomized Clinical Trial Testing the Effect of Digital Behavioral Interventions on Pain and Mental Health Among Adults with Sickle Cell Disease
37. Predicting Hemoglobin Response to Hydroxyurea and Voxelotor in Adults with Sickle Cell Disease
38. Addressing Chronic Anemia in Sickle Cell Disease: Characterizing Erythropoiesis-Stimulating Agent (ESA) Utilization and Practice Patterns Among Providers
39. A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia
40. Correction of the disease phenotype in canine leukocyte adhesion deficiency using ex vivo hematopoietic stem cell gene therapy
41. Hepatocyte growth factor mediates angiopoietin-induced smooth muscle cell recruitment
42. The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia
43. Safety and pharmacokinetics of recombinant factor XIII-A2 administration in patients with congenital factor XIII deficiency
44. WAVE/Scars in platelets
45. Epinephrine acts through erythroid signaling pathways to activate sickle cell adhesion to endothelium via LW-αvβ3 interactions
46. Improvement in quality of life of patients with AL amyloidosis treated with high-dose melphalan and autologous stem cell transplantation
47. Very low levels of donor CD18+ neutrophils following allogeneic hematopoietic stem cell transplantation reverse the disease phenotype in canine leukocyte adhesion deficiency
48. Farnesyltransferase inhibitor tipifarnib is well tolerated, induces stabilization of disease, and inhibits farnesylation and oncogenic/tumor survival pathways in patients with advanced multiple myeloma
49. Isocitrate Dehydrogenase 2 Mutation Drives Bone Marrow Macrophage Dysfunction without a Complete Block in Hematopoietic Differentiation
50. Human NGFR+/VCAM-1+/Mcam+ Bone Marrow-Derived Stromal Cells (NVML) Provide Enhanced Support for Normal Hematopoiesis and Are Disrupted in Myelodysplastic Syndrome
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