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Your search keyword '"Marsh, Steven G. E."' showing total 9 results
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9 results on '"Marsh, Steven G. E."'

1. Genetic testing in severe aplastic anemia is required for optimal hematopoietic cell transplant outcomes

Author

McReynolds, Lisa J., primary, Rafati, Maryam, additional, Wang, Youjin, additional, Ballew, Bari J., additional, Kim, Jung, additional, Williams, Valencia V., additional, Zhou, Weiyin, additional, Hendricks, Rachel M., additional, Dagnall, Casey, additional, Freedman, Neal D., additional, Carter, Brian, additional, Strollo, Sara, additional, Hicks, Belynda, additional, Zhu, Bin, additional, Jones, Kristine, additional, Paczesny, Sophie, additional, Marsh, Steven G. E., additional, Spellman, Stephen R., additional, He, Meilun, additional, Wang, Tao, additional, Lee, Stephanie J., additional, Savage, Sharon A., additional, and Gadalla, Shahinaz M., additional

Published
2022
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2. A core group of structurally similar HLA-DPB1 alleles drives permissiveness after hematopoietic cell transplantation

Author

Arrieta-Bolaños, Esteban, primary, Crivello, Pietro, additional, He, Meilun, additional, Wang, Tao, additional, Gadalla, Shahinaz M., additional, Paczesny, Sophie, additional, Marsh, Steven G. E., additional, Lee, Stephanie J., additional, Spellman, Stephen R., additional, Bolon, Yung-Tsi, additional, and Fleischhauer, Katharina, additional

Published
2022
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3. HLA informs risk predictions after haploidentical stem cell transplantation with posttransplantation cyclophosphamide

Author

Fuchs, Ephraim J., primary, McCurdy, Shannon R., additional, Solomon, Scott R., additional, Wang, Tao, additional, Herr, Megan R., additional, Modi, Dipenkumar, additional, Grunwald, Michael R., additional, Nishihori, Taiga, additional, Kuxhausen, Michelle, additional, Fingerson, Stephanie, additional, McKallor, Caroline, additional, Bashey, Asad, additional, Kasamon, Yvette L., additional, Bolon, Yung-Tsi, additional, Saad, Ayman, additional, McGuirk, Joseph, additional, Paczesny, Sophie, additional, Gadalla, Shahinaz M., additional, Marsh, Steven G. E., additional, Shaw, Bronwen E., additional, Spellman, Stephen R., additional, Lee, Stephanie J., additional, and Petersdorf, Effie W., additional

Published
2022
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4. Identification of a permissible HLA mismatch in hematopoietic stem cell transplantation

Author

Fernandez-Viña, Marcelo A., primary, Wang, Tao, additional, Lee, Stephanie J., additional, Haagenson, Michael, additional, Aljurf, Mahmoud, additional, Askar, Medhat, additional, Battiwalla, Minoo, additional, Baxter-Lowe, Lee-Ann, additional, Gajewski, James, additional, Jakubowski, Ann A., additional, Marino, Susana, additional, Oudshoorn, Machteld, additional, Marsh, Steven G. E., additional, Petersdorf, Effie W., additional, Schultz, Kirk, additional, Turner, E. Victoria, additional, Waller, Edmund K., additional, Woolfrey, Ann, additional, Umejiego, John, additional, Spellman, Stephen R., additional, and Setterholm, Michelle, additional

Published
2014
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5. Amino acid substitution at peptide-binding pockets of HLA class I molecules increases risk of severe acute GVHD and mortality

Author

Pidala, Joseph, primary, Wang, Tao, additional, Haagenson, Michael, additional, Spellman, Stephen R., additional, Askar, Medhat, additional, Battiwalla, Minoo, additional, Baxter-Lowe, Lee Ann, additional, Bitan, Menachem, additional, Fernandez-Viña, Marcelo, additional, Gandhi, Manish, additional, Jakubowski, Ann A., additional, Maiers, Martin, additional, Marino, Susana R., additional, Marsh, Steven G. E., additional, Oudshoorn, Machteld, additional, Palmer, Jeanne, additional, Prasad, Vinod K., additional, Reddy, Vijay, additional, Ringden, Olle, additional, Saber, Wael, additional, Santarone, Stella, additional, Schultz, Kirk R., additional, Setterholm, Michelle, additional, Trachtenberg, Elizabeth, additional, Turner, E. Victoria, additional, Woolfrey, Ann E., additional, Lee, Stephanie J., additional, and Anasetti, Claudio, additional

Published
2013
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6. Donor selection for natural killer cell receptor genes leads to superior survival after unrelated transplantation for acute myelogenous leukemia

Author

Cooley, Sarah, primary, Weisdorf, Daniel J., additional, Guethlein, Lisbeth A., additional, Klein, John P., additional, Wang, Tao, additional, Le, Chap T., additional, Marsh, Steven G. E., additional, Geraghty, Daniel, additional, Spellman, Stephen, additional, Haagenson, Michael D., additional, Ladner, Martha, additional, Trachtenberg, Elizabeth, additional, Parham, Peter, additional, and Miller, Jeffrey S., additional

Published
2010
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7. Donors with group B KIR haplotypes improve relapse-free survival after unrelated hematopoietic cell transplantation for acute myelogenous leukemia

Author

Cooley, Sarah, primary, Trachtenberg, Elizabeth, additional, Bergemann, Tracy L., additional, Saeteurn, Koy, additional, Klein, John, additional, Le, Chap T., additional, Marsh, Steven G. E., additional, Guethlein, Lisbeth A., additional, Parham, Peter, additional, Miller, Jeffrey S., additional, and Weisdorf, Daniel J., additional

Published
2009
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9. HLA-DPB1 matching status has significant implications for recipients of unrelated donor stem cell transplants.

Author

Shaw BE, Marsh SG, Mayor NP, Russell NH, and Madrigal JA

Subjects
Adolescent, Adult, Aged, Child, Child, Preschool, Disease-Free Survival, Female, HLA-DP beta-Chains, Humans, Infant, Leukemia therapy, Lymphocyte Depletion, Male, Middle Aged, Recurrence, Risk Factors, HLA-DP Antigens, Hematopoietic Stem Cell Transplantation, Histocompatibility Testing, Leukemia mortality, Tissue Donors
Abstract

Studies in unrelated donor (UD) hematopoietic stem cell transplantations (HSCT) show an effect of the matching status of HLA-DPB1 on complications. We analyzed 423 UD-HSCT pairs. Most protocols included T-cell depletion (TCD). All pairs had high-resolution tissue typing performed for 6 HLA loci. Two hundred eighty-two pairs were matched at 10 of 10 alleles (29% were DPB1 matched). In 141 HLA-mismatched pairs, 28% were matched for DPB1. In the 10 of 10 matched pairs (n = 282), the 3-year probability of relapse was 61%. This was significantly higher in DPB1-matched pairs (74%) as compared with DPB1-mismatched pairs (56%) (log rank, P = .001). This finding persisted in multivariate analysis. In the group overall (n = 423), relapse was also significantly increased if DPB1 was matched (log rank; P < .001). These results were similar in chronic myeloid leukemia (CML; P < .001) and acute lymphoblastic leukemia (ALL; P = .013). In ALL, DPB1-matched pairs had a significantly worse overall survival (log rank; P = .025). Thus, in recipients of TCD UD-HSCT, a match for DPB1 is associated with a significantly increased risk of disease relapse, irrespective of the matching status for the other HLA molecules. It is possible that this effect is especially apparent following TCD transplantations and invites speculation about the function of DPB1 within the immune system.

Published
2006
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