41 results on '"Mertens, Koen"'
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2. Quantitative phosphoproteomics unveils temporal dynamics of thrombin signaling in human endothelial cells
3. Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease
4. Factor VIII C1 domain residues Lys 2092 and Phe 2093 contribute to membrane binding and cofactor activity
5. Association between beta2-glycoprotein I plasma levels and the risk of myocardial infarction in older men
6. Intracellular cotrafficking of factor VIII and von Willebrand factor type 2N variants to storage organelles
7. Guanine exchange factor RalGDS mediates exocytosis of Weibel-Palade bodies from endothelial cells
8. LDL receptor cooperates with LDL receptor–related protein in regulating plasma levels of coagulation factor VIII in vivo
9. Elevated plasma factor VIII in a mouse model of low-density lipoprotein receptor–related protein deficiency
10. Whole Exome Sequencing and Extended Thrombophilia Testing in Patients with Venous Thromboembolism
11. Two classes of germline genes both derived from the VH1 family direct the formation of human antibodies that recognize distinct antigenic sites in the C2 domain of factor VIII
12. 3-Dimensional structure of membrane-bound coagulation factor VIII: modeling of the factor VIII heterodimer within a 3-dimensional density map derived by electron crystallography
13. Functional mapping of anti–factor IX inhibitors developed in patients with severe hemophilia B
14. Multiple VH genes are used to assemble human antibodies directed toward the A3-C1 domains of factor VIII
15. Activation of factor IX zymogen results in exposure of a binding site for low-density lipoprotein receptor–related protein
16. Cell-Surface Proteomics to Unravel Cytokine-Induced Endothelial Activation
17. Von Willebrand Factor Protects Factor VIII from Rapid Endocytosis Via LDL Receptor-Related Protein By Blocking the Initial Rate-Limiting Cell Surface Binding Step of Factor VIII
18. Factor VIII Region 1811–1818 Is Involved in Factor IXa Binding and Factor VIIIa Stability
19. Factors VIII and V swap fatty feet
20. Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies
21. Modification of An Interactive Surface in the C1 Domain Reduces Immune Responses to FVIII in a Mouse Model of Hemophilia A
22. The N-Terminal Amino Acid Residues Ser764 and Lys773 of the D' Domain of Von Willebrand Factor Contribute to Factor VIII Binding
23. The Role of Factor VIII C Domains in Sorting to Weibel-Palade Bodies
24. Co-Trafficking of Coagulation Factor VIII with Von Willebrand Factor Alters the Macromolecular Structure Inside Secretory Weibel-Palade Bodies
25. Factor VII Activating Protease (FSAP): Functional Implications of the “Marburg-1” Polymorphism.
26. Platelets Contribute to Protein S Cleavage In Vivo.
27. Differential Anticoagulant Effects of Protein S on Vascular Cells and Platelets.
28. Decreased beta2-Glycoprotein I Plasma Levels as a Risk Factor for Myocardial Infarction in Men.
29. Factor VIII C1 Domain Residues 2092–2093 Participate in Membrane Binding
30. PEGylation or Polysialylation Reduces FVIII Binding to LRP Resulting in Prolonged Half-Life in Murine Models.
31. Antiphospholipid Antibodies with LAC Activity That Bind beta2-Glycoprotein I Cause Increased Resistance Against Activated Protein C.
32. LDL Receptor Mediates Effective Endocytosis of Activated Factor V.
33. Effective Factor VIII Endocytosis Is under Conformational Control of von Willebrand Factor.
34. Somatic Mutations in Factor VIII Inhibitors Determine Their Factor VIII Binding and Inhibitory Properties.
35. The Effect of von Willebrand Factor Normandy Mutations on Intracellular Co-Trafficking of Factor VIII to Storage Organelles.
36. Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver
37. Role of Low Density Lipoprotein Receptor in the Clearance of Coagulation Factor VIII In Vivo.
38. The Life Cycle of Coagulation Factor VIII in View of Its Structure and Function
39. A Human Alloantibody Interferes With Binding of Factor IXa to the Factor VIII Light Chain
40. On the Target Specificity of Plasminogen Activator Inhibitor 1: The Role of Heparin, Vitronectin, and the Reactive Site
41. Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease.
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