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12 results on '"Ni, Ming"'

1. Th22 and Tfh Cell Elevation Is Associated with Clinical Response of Photopheresis Therapy in Patients with Steroid-Refractory/ Resistant Graft-Versus-Host Disease (GvHD)

Author

Ding, Yuntian, primary, Wang, Lei, additional, Ni, Ming, additional, Gong, Wenjie, additional, Wang, Sanmei, additional, Neuber, Brigitte, additional, Schubert, Maria-Luisa, additional, Sauer, Tim, additional, Hückelhoven-Krauss, Angela, additional, Luft, Thomas, additional, Hegenbart, Ute, additional, Schönland, Stefan, additional, Eckstein, Volker, additional, Wang, Jishi, additional, Krüger, William Hermann, additional, Müller-Tidow, Carsten, additional, Dreger, Peter, additional, Schmitt, Michael, additional, and Schmitt, Anita, additional

Published
2021
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3. The Effect of Apoptosis Inhibitor Blockade Agents on the Third Generation CD19 CAR T Cells

Author

Yang, Mingya, primary, Wang, Lei, additional, Ni, Ming, additional, Schubert, Maria-Luisa, additional, Neuber, Brigitte, additional, Hückelhoven-Krauss, Angela, additional, Gößmann, Ruben A., additional, Kleist, Christian, additional, Eckstein, Volker, additional, Müller-Tidow, Carsten, additional, Dreger, Peter, additional, Schmitt, Michael, additional, and Schmitt, Anita, additional

Published
2019
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4. Maintaining the Cellular Anti-Viral and Anti-Leukemic Activities in GvHD Patients Undergoing Extracorporeal Photophoresis Therapy

Author

Gößmann, Ruben A., primary, Wang, Lei, additional, Ni, Ming, additional, Yang, Mingya, additional, Luft, Thomas, additional, Hegenbart, Ute, additional, Schönland, Stefan O., additional, Wuchter, Patrick, additional, Eckstein, Volker, additional, Krüger, William Hermann, additional, Yerushalmi, Ronit, additional, Beider, Katia, additional, Nagler, Arnon, additional, Müller-Tidow, Carsten, additional, Dreger, Peter, additional, Schmitt, Michael, additional, and Schmitt, Anita, additional

Published
2019
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5. Development of Potency Assays for Quality Assessment of an Advanced Therapy Medicinal Product: Mitomycin C-Induced Peripheral Blood Mononuclear Cell (MIC) Product

Author

NI, Ming, primary, Wang, Lei, additional, Kleist, Christian, additional, Terness, Peter, additional, Opelz, Gerhard, additional, Morath, Christian, additional, Schaier, Matthias, additional, Müller-Tidow, Carsten, additional, Zeier, Martin, additional, Schmitt, Michael, additional, and Schmitt, Anita, additional

Published
2018
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6. No Inhibition of Anti-Viral and Anti-Leukemia Effects By Extracorporeal Photopheresis Therapy

Author

NI, Ming, primary, Wang, Lei, additional, Hückelhoven, Angela, additional, Sellner, Leopold, additional, Neuber, Brigitte, additional, Hoffmann, Jean-Marc, additional, Luft, Thomas, additional, Hegenbart, Ute, additional, Schönland, Stefan, additional, Wuchter, Patrick, additional, Eckstein, Volker, additional, Krüger, William Hermann, additional, Yerushalmi, Ronit, additional, Nagler, Arnon, additional, Hilgendorf, Inken, additional, Müller-Tidow, Carsten, additional, Ho, Anthony D, additional, Dreger, Peter, additional, Schmitt, Michael, additional, and Schmitt, Anita, additional

Published
2018
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7. Marked Impact of Different Cytokines on Phenotype and Cytotoxic Activity of CD19-Specific CAR T Cells

Author

Hoffmann, Jean-Marc, primary, Wang, Lei, additional, Hückelhoven, Angela, additional, Schmitt, Anita, additional, Gern, Ulrike, additional, Sellner, Leopold, additional, Kleist, Christian, additional, Wenthe, Jessica, additional, Wuchter, Patrick, additional, Schubert, Maria-Luisa, additional, Yoo, Hyeon Joo, additional, Ni, Ming, additional, Hofmann, Susanne, additional, Dreger, Peter, additional, Ho, Anthony D., additional, Loskog, Angelica, additional, and Schmitt, Michael, additional

Published
2016
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8. CD56briCD27+CD11b+/- NK Cells Mediated Remission of Agvhd Via Immunoregulation

Author

Ni, Ming, Zhao, Peng, Kang, Qian, Pan, Chengyun, Hu, Xiuying, Hu, Tianzhen, Fang, Qin, and Wang, Jishi

Abstract

Background: In our previous study, CD56briCD27+CD11b+/- NK cells show the potential of the remission of aGvHD, while the mechanism behind it is still unknown. Thus, in the present study, samples from patient after allo-HSCT within 100 days has been investigated deeply.

Published
2023
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9. BRG1 Regulates Adult B-Cell Acute Lymphoblastic Leukemia Proliferation and Apoptosis By Interacting with c-MYC and Activating PI3K/AKT Pathway

Author

Kang, Qian, Zhao, Peng, Ni, Ming, Fang, Qin, and Wang, Jishi

Abstract

Background and objective：Adult B-cell acute lymphoblastic leukemia（B-ALL）has historically had a dismal prognosis, with limited treatment options and cure rates less than 40%. Only 25% of patients older than 50 years old were alive 5 years after diagnosis, highlighting the need for further improvements in treatment for older adult patients (≥40 years). Recently years, genome profiling revealed that cancer cells frequently depend on chromatin regulatory activities to maintain a malignant phenotype and proliferation. Brahma-related gene 1（BRG1）, a core catalytic ATPase subunits of the SWI/SNF chromatin remodelling complex, has been reported to support oncogenic transcriptional program and sustain leukaemogenic transformation in leukemia. However, the specific role and mechanisms of BRG1 in B-ALL development and progression remains largely unknown. Therefore, elucidating the underlying maintenance mechanisms is essential to develop novel effective treatment strategies.

Published
2023
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12. Biomarkers for Clinical Response of Extracorporeal Photopheresis

Author

Ni, Ming, Wang, Lei, Hückelhoven, Angela, Sellner, Leopold, Hoffmann, Jean-Marc, Luft, Thomas, Hegenbart, Ute, Schönland, Stefan, Kleist, Christian, Sill, Martin, Chen, Bao-an, Wuchter, Patrick, Eckstein, Volker, Krüger, William Hermann, Hilgendorf, Inken, Nagler, Arnon, Müller-Tidow, Carsten, Ho, Anthony D., Dreger, Peter, Schmitt, Michael, and Schmitt, Anita

Abstract

Introduction:Post-transplant morbidity and mortality are majorly determined by GvL effect counter-balanced by GvHD. Treatment with systemic steroids represents the first-line therapy for GvHD, but is associated with increased incidence of infection and relapse. ECP can reduce the extent of GvHD while preserving anti-virus/-tumor activity. However, ECP, a time-consuming and relatively expensive therapy, requires specialized equipment and staff expertise as well as the mechanism of action remains unclear. Therefore, this study was performed to address these unsolved questions.

Published
2017
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