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Your search keyword '"Peñalver, J."' showing total 3 results
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3 results on '"Peñalver, J."'

1. Treatment of Diffuse Large B Cell Lymphoma with CHOP and Rituximab. Results of a Multicenter Study with 236 Patients.

Author

De la Serna, Javier, primary, Ayala, R., additional, Canales, M., additional, Giraldo, P., additional, de la Cruz-Mora, M., additional, Rueda, A., additional, Montalban, C., additional, Queizan, J., additional, Garcia-Vela, J., additional, Feliu, F., additional, Calle, C., additional, Hernandez, B., additional, Hernandez, R., additional, Solano, F., additional, Peñalver, J., additional, Ojanguren, J., additional, Sanchez-Guilarte, J., additional, Morante, C., additional, Nicolas, C., additional, Roman, A., additional, Palomera, L., additional, and Diaz-Mediavilla, J., additional

Published
2005
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2. Long-term results of a phase 2 study of rituximab and bendamustine for mucosa-associated lymphoid tissue lymphoma.

Author

Salar A, Domingo-Domenech E, Panizo C, Nicolás C, Bargay J, Muntañola A, Canales M, Bello JL, Sancho JM, Tomás JF, Rodríguez MJ, Peñalver J, Grande C, Sánchez-Blanco JJ, Palomera L, Arranz R, Conde E, García M, García JF, Caballero D, and Montalbán C

Subjects
Adult, Aged, Aged, 80 and over, Female, Humans, Longitudinal Studies, Lymphoma, B-Cell, Marginal Zone mortality, Male, Middle Aged, Prognosis, Recurrence, Remission Induction, Survival Analysis, Bendamustine Hydrochloride therapeutic use, Lymphoma, B-Cell, Marginal Zone drug therapy, Rituximab therapeutic use
Published
2017
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3. Progressive dysfunction of monocytes associated with iron overload and age in patients with thalassemia major.

Author

Ballart IJ, Estevez ME, Sen L, Diez RA, Giuntoli J, de Miani SA, and Peñalver J

Subjects
Adolescent, Adult, Age Factors, Candida immunology, Chelating Agents pharmacology, Child, Child, Preschool, Female, Humans, Infant, Male, Phagocytosis, Splenectomy, Iron metabolism, Monocytes immunology, Thalassemia immunology
Abstract

We evaluated phagocytic and lytic activities of peripheral blood monocytes (PBMo) from patients with thalassemia major (ThP) using C pseudotropicalis as the target. PBMo from ThP showed decreased lytic activity (P less than .001), whereas the phagocytic activity did not differ from that of the controls. Significant inverse correlations were found between lytic activity of PBMo and age of patients (r2 = .47; P less than .01) and also between lytic activity and serum ferritin levels (r2 = .65; P less than .001). No association was found between lytic activity and other variables (blood transfusion regimens, therapy with desferrioxamine, liver damage, and the presence of sHBAg). Splenectomy showed no positive effect on PBMo functions from ThP. Our results suggest that PBMo from ThP have an intracellular defect in their microbicidal mechanisms associated with iron overload. This cell dysfunction could be responsible, at least in part, for the increased susceptibility to infections reported in ThP.

Published
1986

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