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1. T-cell growth factor production by adult, but not childhood. Acute lymphoblastic leukaemic cells

Author

Chris Matthews, Ram Seshadri, H.A. Moore, and Heddy Zola

Subjects
Interleukin 2, Adult, medicine.medical_specialty, T-cell growth factor, medicine.medical_treatment, hemic and lymphatic diseases, Acute lymphocytic leukemia, Internal medicine, medicine, Humans, Child, Hematology, Cluster of differentiation, business.industry, Growth factor, General Medicine, T lymphocyte, medicine.disease, Phenotype, Leukemia, Lymphoid, Immunology, Acute Disease, Neoplastic Stem Cells, Interleukin-2, business, medicine.drug
Abstract

The production of T-cell growth factor (TCGF) by acute lymphoblastic leukaemia (ALL) cells was determined in seven children and in three adults. A significant production of TCGF by adult, but not childhood, ALL cells was observed. The adult ALL cells were classified as “non-T-non-B” by surface marker analysis. It is suggested that TCGF production may not be confined to the cells of T-lineage.

Published
1984

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