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2. Immune landscape and prognostic index for pancreatic cancer based on TCGA database and in vivo validation

Author

Pan-ling Xu, Chien-shan Cheng, Ting Wang, Shu Dong, and Ping Li

Subjects
Pancreatic cancer, Immune landscape, Prognosis, M0 macrophage, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Highlights M0 macrophages accounted for more than 9.8%, indicating a poor prognosis in pancreatic cancer. M0 macrophages proportion were negatively correlated with CD8 + T cells, and immune scores. M0 macrophages promote pancreatic cancer growth in vivo. Elimination of M0 macrophages may be a promising strategy against PAAD.

Published
2023
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