1. The impact of gender difference on operative time in laparoscopic partial nephrectomy for T1 renal tumor and the utility of retroperitoneal fat thickness as a predictor of operative time
- Author
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Masahiro Yao, Takashi Kawahara, Hiroki Ito, Kazuhide Makiyama, Kimito Osaka, Yumiko Yokomizo, Noboru Nakaigawa, and Koji Izumi
- Subjects
Adult ,Male ,medicine.medical_specialty ,Cancer Research ,medicine.medical_treatment ,Operative Time ,030232 urology & nephrology ,Abdominal Fat ,Logistic regression ,Nephrectomy ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Genetics ,Retroperitoneal space ,Humans ,Partial nephrectomy ,Gender difference ,Retroperitoneal Space ,Laparoscopy ,Carcinoma, Renal Cell ,Aged ,Retrospective Studies ,Sex Characteristics ,medicine.diagnostic_test ,Tumor size ,business.industry ,Retrospective cohort study ,Renal tumor ,Middle Aged ,Kidney Neoplasms ,Surgery ,medicine.anatomical_structure ,Logistic Models ,Treatment Outcome ,Renal cancer ,Oncology ,030220 oncology & carcinogenesis ,Operative time ,Female ,business ,Research Article - Abstract
Background To investigate the impact of biological gender on operative parameters, especially operative time, in laparoscopic partial nephrectomy (LPN) for T1 renal tumor. Methods One hundred and eleven (28 female and 83 male) patients and 64 (20 female and 44 male) patients with renal tumors suspected to be RCC cT1aN0M0 who underwent retroperitoneal and transperitoneal LPN, respectively, were analyzed. The influence of sex on operative factors including retroperitoneal fat tissue thickness, determined on CT, was analyzed. The correlation between operative time and gender was evaluated by unpaired t-test and linear logistic regression model. Results In both retroperitoneal and transperitoneal LPN, the retroperitoneal fat tissue thickness was greater in men than in women. In retroperitoneal LPN, the operative time was significantly longer in men than in women. In contrast, in transperitoneal LPN, no gender difference was observed in regard to the operative time. In retroperitoneal LPN, linear logistic regression assessment showed that gender, retroperitoneal fat tissue thickness, and tumor size were significantly associated with operative time. Coefficient of determination of the prediction model was 0.317. Conclusions The operative time of retroperitoneal LPN is significantly correlated with gender, maximum tumor diameter, and retroperitoneal fat tissue thickness. We have developed a prediction model for the operative time of retroperitoneal LPN based on preoperative parameters. Interestingly, in transperitoneal LPN, a gender difference in operative time was not apparent, and also predicting operative time might be difficult.
- Published
- 2016