6 results on '"Ruiqin Xie"'
Search Results
2. Relationship among atrial fibrillation, the CHA2DS2-VASc score and ischaemic stroke in patients with coronary artery disease: a propensity score matching study in Hebei, China
- Author
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Boqun Shi, Demin Liu, Qian Wang, Xue Geng, Qian Hou, Guoqiang Gu, Ruiqin Xie, and Wei Cui
- Subjects
Atrial fibrillation ,CHA2DS2-VASc score ,Coronary artery disease ,Ischaemic stroke ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Background Recent evidence has shown that the pathogenesis of ischaemic stroke associated with atrial fibrillation (AF) is complex and involves other factors in addition to arrhythmias. The purpose of this study was to investigate the relationship among AF, CHA2DS2-VASc score and ischaemic stroke in patients with coronary artery disease (CAD) in Hebei, China. Methods A total of 2,335 patients with CAD from September 2016 to May 2019 at the Second Hospital of Hebei Medical University were included (mean age 62.73 ± 10.35 years, range 26–92 years; 41.58% female). This was a cross-sectional study, and participants were divided into non-stroke (n = 1997) and ischaemic stroke groups (n = 338). Propensity score matching (PSM) was performed to match ischaemic stroke patients with non-stroke patients in a 1:4 ratio. The relationship among AF, the CHA2DS2-VASc score and ischaemic stroke was evaluated using univariable generalized linear models for different sex, age, body mass index (BMI), CAD and CHA2DS2-VASc score subgroups. Univariable and multivariable generalized linear models were used to evaluate the relationship between AF and ischaemic stroke in the different models. Results Compared with that in the non-stroke group, the prevalence of AF (8.81% vs. 14.20%, P = 0.002) in the ischaemic stroke group was higher. The proportion of patients with ischaemic stroke was significantly different between the AF group and the non-AF group (28.74% vs. 19.04%, P = 0.003). An increasing CHA2DS2-VASc score was associated with a gradual increase in the prevalence of AF (P for trend
- Published
- 2021
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- View/download PDF
3. Relationship among atrial fibrillation, the CHA2DS2-VASc score and ischaemic stroke in patients with coronary artery disease: a propensity score matching study in Hebei, China
- Author
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Demin Liu, Wei Cui, Guoqiang Gu, Qian Hou, Xue Geng, Ruiqin Xie, Boqun Shi, and Qian Wang
- Subjects
medicine.medical_specialty ,CHA2DS2-VASc score ,business.industry ,Subgroup analysis ,Atrial fibrillation ,medicine.disease ,Coronary artery disease ,Cardiac surgery ,RC666-701 ,Internal medicine ,CHA2DS2–VASc score ,Propensity score matching ,medicine ,Cardiology ,Diseases of the circulatory (Cardiovascular) system ,cardiovascular diseases ,Cardiology and Cardiovascular Medicine ,business ,Ischaemic stroke ,Body mass index ,Angiology - Abstract
Background Recent evidence has shown that the pathogenesis of ischaemic stroke associated with atrial fibrillation (AF) is complex and involves other factors in addition to arrhythmias. The purpose of this study was to investigate the relationship among AF, CHA2DS2-VASc score and ischaemic stroke in patients with coronary artery disease (CAD) in Hebei, China. Methods A total of 2,335 patients with CAD from September 2016 to May 2019 at the Second Hospital of Hebei Medical University were included (mean age 62.73 ± 10.35 years, range 26–92 years; 41.58% female). This was a cross-sectional study, and participants were divided into non-stroke (n = 1997) and ischaemic stroke groups (n = 338). Propensity score matching (PSM) was performed to match ischaemic stroke patients with non-stroke patients in a 1:4 ratio. The relationship among AF, the CHA2DS2-VASc score and ischaemic stroke was evaluated using univariable generalized linear models for different sex, age, body mass index (BMI), CAD and CHA2DS2-VASc score subgroups. Univariable and multivariable generalized linear models were used to evaluate the relationship between AF and ischaemic stroke in the different models. Results Compared with that in the non-stroke group, the prevalence of AF (8.81% vs. 14.20%, P = 0.002) in the ischaemic stroke group was higher. The proportion of patients with ischaemic stroke was significantly different between the AF group and the non-AF group (28.74% vs. 19.04%, P = 0.003). An increasing CHA2DS2-VASc score was associated with a gradual increase in the prevalence of AF (P for trend P = 0.087). Conclusion In our cross-sectional study, after adjustment for confounding factors, there was no association between AF and ischaemic stroke. The increased risk of ischaemic stroke associated with AF was attenuated by atherosclerotic factors. Our study supports the current view that enhanced control of modifiable cardiovascular risk factors in patients with AF is essential.
- Published
- 2021
4. Relationship among atrial fibrillation, the CHA
- Author
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Boqun, Shi, Demin, Liu, Qian, Wang, Xue, Geng, Qian, Hou, Guoqiang, Gu, Ruiqin, Xie, and Wei, Cui
- Subjects
Adult ,Aged, 80 and over ,Male ,China ,CHA2DS2-VASc score ,Coronary Artery Disease ,Middle Aged ,Prognosis ,Risk Assessment ,Atrial fibrillation ,Decision Support Techniques ,Cross-Sectional Studies ,Predictive Value of Tests ,Risk Factors ,Prevalence ,Humans ,Female ,cardiovascular diseases ,Propensity Score ,Ischaemic stroke ,Aged ,Ischemic Stroke ,Research Article - Abstract
Background Recent evidence has shown that the pathogenesis of ischaemic stroke associated with atrial fibrillation (AF) is complex and involves other factors in addition to arrhythmias. The purpose of this study was to investigate the relationship among AF, CHA2DS2-VASc score and ischaemic stroke in patients with coronary artery disease (CAD) in Hebei, China. Methods A total of 2,335 patients with CAD from September 2016 to May 2019 at the Second Hospital of Hebei Medical University were included (mean age 62.73 ± 10.35 years, range 26–92 years; 41.58% female). This was a cross-sectional study, and participants were divided into non-stroke (n = 1997) and ischaemic stroke groups (n = 338). Propensity score matching (PSM) was performed to match ischaemic stroke patients with non-stroke patients in a 1:4 ratio. The relationship among AF, the CHA2DS2-VASc score and ischaemic stroke was evaluated using univariable generalized linear models for different sex, age, body mass index (BMI), CAD and CHA2DS2-VASc score subgroups. Univariable and multivariable generalized linear models were used to evaluate the relationship between AF and ischaemic stroke in the different models. Results Compared with that in the non-stroke group, the prevalence of AF (8.81% vs. 14.20%, P = 0.002) in the ischaemic stroke group was higher. The proportion of patients with ischaemic stroke was significantly different between the AF group and the non-AF group (28.74% vs. 19.04%, P = 0.003). An increasing CHA2DS2-VASc score was associated with a gradual increase in the prevalence of AF (P for trend
- Published
- 2020
5. High levels of serum β2-microglobulin predict severity of coronary artery disease
- Author
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Haijuan Hu, Ruiqin Xie, Wei Cui, Ximiao He, Hongmei Zheng, Jidong Zhang, Guoqiang Gu, Xiaohong Yang, and Ling You
- Subjects
Male ,China ,medicine.medical_specialty ,Coronary Artery Disease ,030204 cardiovascular system & hematology ,Coronary Angiography ,Severity of Illness Index ,Severity ,Coronary artery disease ,03 medical and health sciences ,0302 clinical medicine ,Predictive Value of Tests ,Internal medicine ,Severity of illness ,Prevalence ,medicine ,Humans ,cardiovascular diseases ,030212 general & internal medicine ,Risk factor ,β2-Microglobulin ,Aged ,Framingham Risk Score ,Receiver operating characteristic ,business.industry ,Case-control study ,Odds ratio ,Middle Aged ,Prognosis ,medicine.disease ,Confidence interval ,Up-Regulation ,ROC Curve ,Area Under Curve ,Case-Control Studies ,Cardiology ,Female ,beta 2-Microglobulin ,Cardiology and Cardiovascular Medicine ,business ,Biomarkers ,Research Article - Abstract
Background The identification of new risk factors for coronary artery disease (CAD) is increasingly sought in an effort to tackle this threatening disease. β2-microglobulin (B2M) is reported to associate with peripheral arterial disease and adverse cardiovascular outcomes. However, the association between B2M and cardiovascular disease remains under-researched. This study evaluated the effects of B2M on CAD without renal dysfunction. Methods One thousand seven hundred sixty-two subjects (403 non-CAD subjects and 1,359 CAD subjects) were investigated. Fasting samples were collected to determine B2M level. The Gensini and SYNTAX scores were used to assess the severity of CAD. Results CAD subjects were significantly higher in serum B2M level comparing with non-CAD subjects (1.25 ± 0.46 vs 1.14 ± 0.28 mg/L, p
- Published
- 2017
6. High levels of serum β2-microglobulin predict severity of coronary artery disease.
- Author
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Ling You, Ruiqin Xie, Haijuan Hu, Guoqiang Gu, Hongmei Zheng, Jidong Zhang, Xiaohong Yang, Ximiao He, Wei Cui, You, Ling, Xie, Ruiqin, Hu, Haijuan, Gu, Guoqiang, Zheng, Hongmei, Zhang, Jidong, Yang, Xiaohong, He, Ximiao, and Cui, Wei
- Subjects
BETA 2-microglobulin ,CORONARY disease ,MICROGLOBULINS ,ARTERIAL diseases ,C-reactive protein ,QUALITY of life - Abstract
Background: The identification of new risk factors for coronary artery disease (CAD) is increasingly sought in an effort to tackle this threatening disease. β2-microglobulin (B2M) is reported to associate with peripheral arterial disease and adverse cardiovascular outcomes. However, the association between B2M and cardiovascular disease remains under-researched. This study evaluated the effects of B2M on CAD without renal dysfunction.Methods: One thousand seven hundred sixty-two subjects (403 non-CAD subjects and 1,359 CAD subjects) were investigated. Fasting samples were collected to determine B2M level. The Gensini and SYNTAX scores were used to assess the severity of CAD.Results: CAD subjects were significantly higher in serum B2M level comparing with non-CAD subjects (1.25 ± 0.46 vs 1.14 ± 0.28 mg/L, p < 0.001). Serum B2M level was a risk factor of CAD after adjusting potential confounders (Odds Ratio (OR) = 2.363, 95% confidence interval (CI): 1.467-3.906, p = 0.001). Receiver operating characteristics (ROC) showed B2M level moderately predicted diagnosis of CAD (the area under the ROC curve (AUC) = 0.608, 95% CI: 0.577-0.639, p < 0.001). Furthermore, serum B2M level was positively associated with Gensini score system, SYNTAX score system and the number of disease vessels (NDV ≥ 2).Conclusions: The significant association between serum B2M and CAD suggests that B2M could be a biomarker for CAD. [ABSTRACT FROM AUTHOR]- Published
- 2017
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