1. The impact of cardiomotor rehabilitation on endothelial function in elderly patients with chronic heart failure
- Author
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Juming Chen, Shenhong Gu, Yanling Song, Xinbo Ji, Wangyuan Zeng, Xiaoxi Wang, Yachun Wang, and Qingfeng Feng
- Subjects
Heart failure ,Chronic heart failure ,Exercise rehabilitation ,Endothelial progenitor cells ,PI3K/AKT ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Background To explore the effects of cardiac exercise rehabilitation on peripheral blood endothelial progenitor cells (EPC) in elderly patients with chronic heart failure. Methods 80 elderly patients with chronic heart failure were selected from March 2017 to March 2019 and randomly divided into two groups (N = 40). The control group was treated routinely and walked freely for 30–60 min every day. The patients in the exercise rehabilitation group developed a cardiac exercise rehabilitation plan. Then, cardiac function and peripheral blood B-natriuretic peptide (BNP) levels in the two groups were compared. The cell viability, proliferation, apoptosis, and invasion ability of EPCs were detected. The levels of the PI3K/AKT pathway and eNOS and VEGF were compared. Results There were no significant differences in all indexes between the two groups before treatment (P > 0.05), and both improved significantly after treatment (P more...
- Published
- 2021
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