1. Power of computed-tomography-defined sarcopenia for prediction of morbidity after pancreaticoduodenectomy
- Author
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Nicolas Linder, Alexander Schaudinn, Katharina Langenhan, Felix Krenzien, Hans-Michael Hau, Christian Benzing, Georgi Atanasov, Moritz Schmelzle, Thomas Kahn, Harald Busse, Michael Bartels, Ulf Neumann, and Georg Wiltberger
- Subjects
Postoperative pancreatic fistula ,Sarcopenia ,Mean muscle attenuation ,Fat segmentation ,Computed tomography ,Medical technology ,R855-855.5 - Abstract
Abstract Background The goal of our study was to evaluate the current approach in prediction of postoperative major complications after pancreaticoduodenectomy (PD), especially symptomatic pancreatic fistula (POPF), using parameters derived from computed tomography (CT). Methods Patients after PD were prospectively collected in a database of the local department of surgery and all patients with CT scans available were assessed in this study. CT parameters were measured at the level of the intervertebral disc L3/L4 and consisted of the areas of the visceral adipose tissue (AVAT), the diameters of the pancreatic parenchyma (DPP) and the pancreatic duct (DPD), the areas of ventral abdominal wall muscle (AMVEN), psoas muscle (AMPSO), paraspinal muscle (AMSPI), total muscle (AMTOT), as well as the mean muscle attenuation (MA) and skeletal muscle index (SMI). Mann-Whitney-U Test for two independent samples and binary logistic regression were used for statistical analysis. Results One hundred thirty-nine patients (55 females, 84 males) were included. DPD was 2.9 mm (Range 0.7–10.7) on median and more narrow in patients with complications equal to or greater stadium IIIb (p
- Published
- 2019
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