1. Temporal trends of dialysis requiring acute kidney injury after orthotopic cardiac and liver transplant hospitalizations
- Author
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Rocco Ferrandino, Ioannis Konstantinidis, Madhav C. Menon, Sunil Kamat, Girish N. Nadkarni, Shanti Patel, Achint Patel, Aparna Saha, Kinsuk Chauhan, Priti Poojary, Pranav S. Garimella, and Charuhas V. Thakar
- Subjects
Nephrology ,Male ,Cardiac transplant ,Kidney Disease ,Time Factors ,medicine.medical_treatment ,030232 urology & nephrology ,030204 cardiovascular system & hematology ,Liver transplantation ,lcsh:RC870-923 ,urologic and male genital diseases ,Cohort Studies ,0302 clinical medicine ,Epidemiology ,Liver transplant ,Liver Disease ,Acute kidney injury ,Urology & Nephrology ,Acute Kidney Injury ,Middle Aged ,female genital diseases and pregnancy complications ,3. Good health ,Hospitalization ,Female ,6.4 Surgery ,Research Article ,Adult ,medicine.medical_specialty ,Adolescent ,Clinical Sciences ,Renal and urogenital ,Outcomes ,03 medical and health sciences ,Young Adult ,Clinical Research ,Renal Dialysis ,Internal medicine ,medicine ,Humans ,Mortality ,Dialysis ,Aged ,Retrospective Studies ,Transplantation ,business.industry ,Evaluation of treatments and therapeutic interventions ,Odds ratio ,Organ Transplantation ,medicine.disease ,lcsh:Diseases of the genitourinary system. Urology ,Comorbidity ,Liver Transplantation ,Good Health and Well Being ,Heart Transplantation ,business ,Solid organ transplantation ,Digestive Diseases - Abstract
Background The epidemiology and outcomes of acute kidney injury (AKI) in prevalent non-renal solid organ transplant recipients is unknown. Methods We assessed the epidemiology of trends in acute kidney injury (AKI) in orthotopic cardiac and liver transplant recipients in the United States. We used the Nationwide Inpatient Sample to evaluate the yearly incidence trends (2002 to 2013) of the primary outcome, defined as AKI requiring dialysis (AKI-D) in hospitalizations after cardiac and liver transplantation. We also evaluated the trend and impact of AKI-D on hospital mortality and adverse discharge using adjusted odds ratios (aOR). Results The proportion of hospitalizations with AKI (9.7 to 32.7% in cardiac and 8.5 to 28.1% in liver transplant hospitalizations; ptrend
- Published
- 2017