8 results on '"Ron de Graaf"'
Search Results
2. The longitudinal association between lifetime mental disorders and first onset or recurrent suicide ideation
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Derek de Beurs, Margreet ten Have, Pim Cuijpers, and Ron de Graaf
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Suicidal behavior ,Comorbidity ,Epidemiology ,Psychiatry ,RC435-571 - Abstract
Abstract Background Although the cross-sectional association between mental disorders and suicide ideation is well studied, less is known about the prospective association. In this paper, we estimated among those without 12-month suicide ideation at baseline, the association between a wide variety of common mental disorders at baseline and suicide ideation within the 6-year follow-up period, after controlling for history of other mental disorders and demographic variables. Methods Data were used from the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2), a prospective representative adult cohort study with baseline (n = 6646) with a 6-year follow-up period. Lifetime mental disorders were assessed at baseline with the Composite International Diagnostic Interview 3.0. Within the longitudinal design, participants with first time or recurrent suicide ideation were defined follows: having no suicide ideation in the 12 months before the baseline assessment, and reporting to have had seriously thought about suicide between baseline and the 6-year follow-up period. Multiple logistical regression was used to estimate the longitudinal association between suicide ideation and a specific mental disorder while controlling for comorbidity and baseline variables. To account for the prevalence of a disorder in the population, for each disorder, the population attributable risk proportion (PARP) was calculated. Results 2.9% (n = 132) of the participants that did not report suicide ideation in the past 12 months at baseline reported suicide ideation at follow-up. Of these 132 cases, 81 (61%) experienced suicide ideation for the first time in their lives and could be viewed as first onset cases. 51 (39%) reported recurrent suicide ideation. After controlling for comorbidity, the only two disorders that were significantly related to suicide ideation at follow-up were lifetime major depressive disorder (MDD) and generalized anxiety disorder (GAD). PARP for MDD was 47.8 and 16.6% for GAD. Conclusions After controlling for all other mental disorders, a lifetime history of MDD and GAD were related to suicide ideation at follow-up. For clinical practice, this indicates that patients with a history of MDD or GAD stay vulnerable for suicide ideation, even though they did not report suicide ideation in the past year.
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- 2019
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3. Risk factors for suicidal thoughts in informal caregivers: results from the population-based Netherlands mental health survey and incidence Study-2 (NEMESIS-2)
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Karlijn J. Joling, Margreet ten Have, Ron de Graaf, and Siobhan T. O’Dwyer
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Informal caregivers ,Suicidal ideation ,Suicidal thoughts ,Risk factors ,Population study ,Psychiatry ,RC435-571 - Abstract
Abstract Background Previous research suggests that family caregivers contemplate suicide at a higher rate than the general population. Much of this research has been disease specific and in relatively small samples. This study aimed to compare suicidal thoughts between non-caregivers and informal caregivers of people with a variety of conditions, in a large representative sample, and to identify significant risk factors. Methods The general population study NEMESIS-2 (N at baseline = 6646) included 1582 adult caregivers at the second wave (2010–2012) who also participated at the third wave (2013–2015). Suicidal thoughts were assessed over 4 years, with the Suicidality Module of the Composite International Diagnostic Interview 3.0. The presence of suicidal thoughts was estimated and risk factors for suicidal thoughts were assessed with logistic regression analyses adjusted for age and gender. Results Thirty-six informal caregivers (2.9%) reported suicidal thoughts during the 4 year study period. The difference between caregivers and non-caregivers (3.0%) was not significant. Among caregivers, significant risk factors for suicidal thoughts included being unemployed, living without a partner, having lower levels of social support, having a chronic physical disorder, a mood disorder or an anxiety disorder, and having impaired social, physical and emotional functioning. These risk factors were also found in non-caregivers. No caregiving-related characteristics were associated with suicidal thoughts. Conclusion There was no elevated rate of suicidal thoughts in caregivers and risk factors for suicidal thoughts in caregivers were consistent with risk factors in non-caregivers. No association between caregiving characteristics and suicidal thoughts was found. Caregivers with limited resources and in poorer health might still benefit from prevention and intervention efforts.
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- 2019
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4. Borderline personality symptoms and work performance: a population-based survey
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Trees T. Juurlink, Margreet ten Have, Femke Lamers, Hein J. F. van Marle, Johannes R. Anema, Ron de Graaf, and Aartjan T. F. Beekman
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Borderline personality symptoms ,Public health ,Employment ,Work performance ,Occupational health ,Psychiatry ,RC435-571 - Abstract
Abstract Background This study aims to elucidate the interplay between borderline personality symptoms and working conditions as a pathway for impaired work performance among workers in the general population. Methods Cross-sectional data from the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2) were used, including 3672 workers. Borderline personality symptoms were measured with the International Personality Disorder Examination (IPDE) questionnaire. Working conditions (decision latitude, psychological job demands, job security and co-worker support) were assessed with the Job Content Questionnaire (JCQ). Impaired work performance was assessed as total work loss days per month, defined as the sum of days of three types of impaired work performance (inability to work, cut-down to work, and diminished quality at work). These were assessed with the WHO Disability Assessment Schedule (WHO-DAS). Common mental disorders (CMD) were assessed with the Composite International Diagnostic Interview (CIDI). Results Number of borderline personality symptoms was consistently associated with impaired work performance, even after controlling for type or number of adverse working conditions and co-occurrence of CMD. Borderline personality symptoms were associated with low decision latitude, job insecurity and low co-worker support. The relationship between borderline personality symptoms and work performance diminished slightly after controlling for type or number of working conditions. Conclusions The current study shows that having borderline personality symptoms is a unique determinant of work performance. This association seems partially explained through the impact of borderline personality symptoms on working conditions. Future studies are warranted to study causality and should aim at diminishing borderline personality symptoms and coping with working conditions.
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- 2018
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5. Risk factors for suicidal thoughts in informal caregivers: results from the population-based Netherlands mental health survey and incidence Study-2 (NEMESIS-2)
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Margreet ten Have, Ron de Graaf, Siobhan O'Dwyer, Karlijn J. Joling, General practice, APH - Aging & Later Life, APH - Quality of Care, APH - Digital Health, and APH - Mental Health
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Adult ,Male ,lcsh:RC435-571 ,Population ,Suicidal thoughts ,Social support ,Suicidal ideation ,lcsh:Psychiatry ,medicine ,Humans ,education ,Physical disorder ,Aged ,Netherlands ,education.field_of_study ,Mood Disorders ,Family caregivers ,Incidence ,Social Support ,Middle Aged ,medicine.disease ,Anxiety Disorders ,Mental health ,Informal caregivers ,Psychiatry and Mental health ,Mood ,Caregivers ,Risk factors ,Female ,medicine.symptom ,Psychology ,Population study ,Anxiety disorder ,Research Article ,Clinical psychology - Abstract
Background Previous research suggests that family caregivers contemplate suicide at a higher rate than the general population. Much of this research has been disease specific and in relatively small samples. This study aimed to compare suicidal thoughts between non-caregivers and informal caregivers of people with a variety of conditions, in a large representative sample, and to identify significant risk factors. Methods The general population study NEMESIS-2 (N at baseline = 6646) included 1582 adult caregivers at the second wave (2010–2012) who also participated at the third wave (2013–2015). Suicidal thoughts were assessed over 4 years, with the Suicidality Module of the Composite International Diagnostic Interview 3.0. The presence of suicidal thoughts was estimated and risk factors for suicidal thoughts were assessed with logistic regression analyses adjusted for age and gender. Results Thirty-six informal caregivers (2.9%) reported suicidal thoughts during the 4 year study period. The difference between caregivers and non-caregivers (3.0%) was not significant. Among caregivers, significant risk factors for suicidal thoughts included being unemployed, living without a partner, having lower levels of social support, having a chronic physical disorder, a mood disorder or an anxiety disorder, and having impaired social, physical and emotional functioning. These risk factors were also found in non-caregivers. No caregiving-related characteristics were associated with suicidal thoughts. Conclusion There was no elevated rate of suicidal thoughts in caregivers and risk factors for suicidal thoughts in caregivers were consistent with risk factors in non-caregivers. No association between caregiving characteristics and suicidal thoughts was found. Caregivers with limited resources and in poorer health might still benefit from prevention and intervention efforts.
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- 2019
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6. Prevalence rates of borderline personality disorder symptoms: a study based on the Netherlands Mental Health Survey and Incidence Study-2
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Ad Kaasenbrood, Marloes Kleinjan, Saskia van Dorsselaer, Roel Verheul, Marlous Tuithof, Ron de Graaf, and Margreet ten Have
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Adult ,Male ,medicine.medical_specialty ,Health service use ,Borderline personality disorder symptoms ,Population ,Population survey ,Comorbidity ,behavioral disciplines and activities ,Disability Evaluation ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Prevalence of mental disorders ,Borderline Personality Disorder ,mental disorders ,Prevalence ,medicine ,Humans ,Disabled Persons ,Psychiatry ,education ,Borderline personality disorder ,Aged ,Netherlands ,School Health Services ,education.field_of_study ,Disability ,Mental Disorders ,Middle Aged ,Patient Acceptance of Health Care ,medicine.disease ,Health Surveys ,Mental health ,030227 psychiatry ,Diagnostic and Statistical Manual of Mental Disorders ,Substance abuse ,Psychiatry and Mental health ,National Comorbidity Survey ,Anxiety ,Female ,medicine.symptom ,Psychology ,030217 neurology & neurosurgery ,Research Article ,Clinical psychology - Abstract
Background Despite increasing knowledge of the prevalence of borderline personality disorder (BPD) in the general population, and rising awareness of mental disorders both as a categorical and a dimensional construct, research is still lacking on the prevalence of the number of BPD symptoms and their associated consequences, such as comorbidity, disability, and the use of mental health services) in the general population. Methods Data were obtained from the second wave of the Netherlands Mental Health Survey and Incidence Study-2 (N = 5303), a nationally representative face-to-face survey of the general population. BPD symptoms were measured by means of questions from the International Personality Disorder Examination. Comorbidity of common mental disorders was assessed with the Composite International Diagnostic Interview version 3.0. Results Of the total population studied, 69.9 % reported no BPD symptoms, while 25.2 % had 1–2 symptoms, 3.8 % had 3–4 symptoms, and 1.1 % had ≥ 5 BPD symptoms. The number of BPD symptoms reported was found to be positively associated with not living with a partner, having no paid job, and/or having a comorbid mood, anxiety or substance use disorder. Even after adjustment for sociodemographic characteristics and comorbidity, the number of BPD symptoms turned out to be uniquely associated with disability. It also showed a positive relationship with using services for dealing with mental health problems, although this relationship was strongly affected by the presence of comorbid disorders. Conclusions Because even a relatively low number of BPD symptoms appears to be associated with psychiatric comorbidity and functional disability, not only full-blown BPD but also subthreshold levels of BPD symptoms need to be identified in clinical practice and research.
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- 2016
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7. Exposure to environmental factors increases connectivity between symptom domains in the psychopathology network
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Nicole Gunther, Maarten Bak, Ruud van Winkel, Margreet ten Have, Jim van Os, Martine van Nierop, Sinan Guloksuz, Roselind Lieb, Saskia van Dorsselaer, Hans-Ulrich Wittchen, Ron de Graaf, Department Clinical Psychology, RS-Research Line Clinical psychology (part of IIESB program), Psychiatrie & Neuropsychologie, RS: MHeNs - R2 - Mental Health, Promovendi MHN, Ondersteunend personeel MHN, MUMC+: MA Psychiatrie (3), and MUMC+: Hersen en Zenuw Centrum (3)
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Adult ,Male ,Psychosis ,medicine.medical_specialty ,Adolescent ,Substance-Related Disorders ,Epidemiology ,Population ,Environment ,Social Environment ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,medicine ,Humans ,Psychiatry ,education ,Depression (differential diagnoses) ,Netherlands ,education.field_of_study ,Psychopathology ,Depression ,Incidence ,Mental Disorders ,Social environment ,Environmental exposure ,medicine.disease ,Health Surveys ,Mental health ,030227 psychiatry ,Diagnostic and Statistical Manual of Mental Disorders ,Psychiatry and Mental health ,Female ,Symptom Assessment ,Psychology ,030217 neurology & neurosurgery ,Developmental psychopathology ,Research Article ,Clinical psychology - Abstract
Background: We investigated to what degree environmental exposure (childhood trauma, urbanicity, cannabis use, and discrimination) impacts symptom connectivity using both continuous and categorical measures of psychopathology.Methods: Outcomes were continuous symptom dimensions of self-reported psychopathology using the Self-report Symptom Checklist-90-R in 3021 participants from The Early Developmental Stages of the Psychopathology (EDSP) study and binary DSM-III-R categories of mental disorders and a binary measure of psychotic symptoms in 7076 participants from The Netherlands Mental Health Survey and Incidence Study (NEMESIS-1). For each symptom dimension in the EDSP and mental disorder in the NEMESIS-1 as the dependent variable, regression analyses were carried out including each of the remaining symptom dimensions/mental disorders and its interaction with cumulative environmental risk load (the sum score of environmental exposures) as independent variables.Results: All symptom dimensions in the EDSP and related diagnostic categories in the NEMESIS-1 were strongly associated with each other, and environmental exposures increased the degree of symptom connectivity in the networks in both cohorts.Conclusions: Our findings showing strong connectivity across symptom dimensions and related binary diagnostic constructs in two independent population cohorts provide further evidence for the conceptualization of psychopathology as a contextually sensitive network of mutually interacting symptoms.
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- 2016
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8. Emotional disorders among informal caregivers in the general population: target groups for prevention
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Marlous Tuithof, Margreet ten Have, Ron de Graaf, and Saskia van Dorsselaer
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Adult ,Male ,Mood and anxiety disorders ,medicine.medical_specialty ,Population ,Emotional disorder ,Target groups ,Risk indicators ,Risk Factors ,General population study ,medicine ,Prevalence ,Humans ,education ,Psychiatry ,Reference group ,Netherlands ,education.field_of_study ,Mood Disorders ,Social Support ,Middle Aged ,medicine.disease ,Mental health ,Anxiety Disorders ,Health Surveys ,Informal care ,Psychiatry and Mental health ,Mood ,Caregivers ,Female ,Psychology ,Anxiety disorder ,Clinical psychology ,Research Article - Abstract
Background There are indications that informal caregiving negatively impacts caregivers’ mental health, but this was hardly examined using diagnoses of mental disorders and most studies used convenience samples without including non-caregivers as reference group. We examine whether informal caregivers more often have any emotional disorder, i.e. mood or anxiety disorder, than non-caregivers. Identify key risk indicators for any emotional disorder among informal caregivers in the general population. Methods Data were used from the second wave of the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2), a nationally representative face-to-face survey (n = 5,303; aged 21–68). Respondents were defined as informal caregiver when they provided unpaid care in the 12 months preceding the second wave to a family member, partner or friend who needed care because of physical or mental problems, or ageing. Twelve-month DSM-IV diagnoses of emotional disorders were assessed using the Composite International Diagnostic Interview 3.0. Key risk indicators were identified using the following aspects: prevalence, odds ratio, attributable risk proportion, and number needed to treat. Sociodemographic, caregiving-related and other characteristics were considered as risk indicators. Results In the past year, 31.1% of the respondents provided informal care, which ranged in time spent (8 or more hours/week: 32.1%) and duration (longer than 1 year: 48.7%). Informal caregiving was not associated with having any 12-month emotional disorder. Among caregivers, giving care to a first-degree relative, partner or close friend and giving emotional support increased the risk for any emotional disorder. Moreover, using all aspects, target groups were identified for prevention: caregivers without a job, living without a partner, and with a lack of social support. Conclusions Although informal caregivers do not have an increased risk of emotional disorders, key risk indicators were identified using four aspects. Especially informal caregivers with limited resources (unemployment, living without a partner, lack of social support) may benefit from targeted prevention whereas general prevention measures may be desirable for carers with a burdensome care situation (giving care to a close loved one or providing emotional support).
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