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Abstract Objective Tuberculosis (TB) remains an important public health concern in western China. This study aimed to explore and analyze the spatial and temporal distribution characteristics of TB reported incidence in 12 provinces and municipalities in western China and to construct the optimal models for prediction, which would provide a reference for the prevention and control of TB and the optimization of related health policies. Methods We collected monthly data on TB reported incidence in 12 provinces and municipalities in western China and used ArcGIS software to analyze the spatial and temporal distribution characteristics of TB reported incidence. We applied the seasonal index method for the seasonal analysis of TB reported incidence and then established the SARIMA and Holt-Winters models for TB reported incidence in 12 provinces and municipalities in western China. Results The reported incidence of TB in 12 provinces and municipalities in western China showed apparent spatial clustering characteristics, and Moran’s I was greater than 0 (p 0.05). Conclusions As a hotspot of reported TB incidence, Tibet should continue to strengthen government leadership and policy support, explore TB intervention strategies and causes. The optimal prediction models we developed for reported TB incidence in 12 provinces and municipalities in western China were different.

Abstract Background This study aimed to construct a more accurate model to forecast the incidence of hand, foot, and mouth disease (HFMD) in mainland China from January 2008 to December 2019 and to provide a reference for the surveillance and early warning of HFMD. Methods We collected data on the incidence of HFMD in mainland China between January 2008 and December 2019. The SARIMA, SARIMA-BPNN, and SARIMA-PSO-BPNN hybrid models were used to predict the incidence of HFMD. The prediction performance was compared using the mean absolute error(MAE), mean squared error(MSE), root mean square error (RMSE), mean absolute percentage error (MAPE), and correlation analysis. Results The incidence of HFMD in mainland China from January 2008 to December 2019 showed fluctuating downward trends with clear seasonality and periodicity. The optimal SARIMA model was SARIMA(1,0,1)(2,1,2)[12], with Akaike information criterion (AIC) and Bayesian Schwarz information criterion (BIC) values of this model were 638.72, 661.02, respectively. The optimal SARIMA-BPNN hybrid model was a 3-layer BPNN neural network with nodes of 1, 10, and 1 in the input, hidden, and output layers, and the R-squared, MAE, and RMSE values were 0.78, 3.30, and 4.15, respectively. For the optimal SARIMA-PSO-BPNN hybrid model, the number of particles is 10, the acceleration coefficients c1 and c2 are both 1, the inertia weight is 1, the probability of change is 0.95, and the values of R-squared, MAE, and RMSE are 0.86, 2.89, and 3.57, respectively. Conclusions Compared with the SARIMA and SARIMA-BPNN hybrid models, the SARIMA-PSO-BPNN model can effectively forecast the change in observed HFMD incidence, which can serve as a reference for the prevention and control of HFMD.