1. Evidence of reduced treatment adherence among HIV infected paediatric and adolescent populations in Nairobi at the onset of the UNAIDS Universal Test and Treat Program
- Author
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Rachel N. Musoke, Fred Wamunyokoli, Erastus Muniu, Elijah M. Songok, and Joseph Mbugua Kabogo
- Subjects
Male ,0301 basic medicine ,Pediatrics ,Treatment adherence ,Universal test and treat ,Human immunodeficiency virus (HIV) ,lcsh:Medicine ,HIV Infections ,medicine.disease_cause ,0302 clinical medicine ,Hiv infected ,Outcome Assessment, Health Care ,030212 general & internal medicine ,Program Development ,Child ,Children ,lcsh:QH301-705.5 ,General Medicine ,Antiretroviral therapy ,Research Note ,Virologic failure ,Child, Preschool ,Female ,medicine.medical_specialty ,Adolescent ,United Nations ,Anti-HIV Agents ,World Health Organization ,General Biochemistry, Genetics and Molecular Biology ,World health ,Medication Adherence ,03 medical and health sciences ,medicine ,Humans ,lcsh:Science (General) ,Retrospective Studies ,90-90-90 ,business.industry ,lcsh:R ,Infant ,HIV ,Retrospective cohort study ,Kenya ,030112 virology ,Increased risk ,lcsh:Biology (General) ,Adherence ,Test and treat ,business ,lcsh:Q1-390 - Abstract
Objective We conducted a retrospective cohort study to evaluate the efficacy of the World Health Organization (WHO) “Universal Test and Treat” (UTT) policy, initiated in Kenya in September 2016. Under this policy, every human immunodeficiency virus (HIV)-infected person should be initiated on antiretroviral therapy (ART). We compared intra- and inter-group viral suppression and ART adherence rates for pre-UTT (initiated on ART in March–August 2016) and UTT groups (initiated in September 2016). The study was conducted in a community outreach Program in Nairobi with 3500 HIV-infected children enrolled. Results 122 children and adolescents were initiated on first-line ART pre-UTT, and 197 during the UTT period. The 6 month viral suppression rate was 79.7% pre-UTT versus 76.6% UTT (P
- Published
- 2018
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