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2 results on '"Shinsuke Miyano"'

1. Seroprevalence of mumps before the introduction of mumps-containing vaccine in Lao PDR: results from a nationwide cross-sectional population-based survey

Author

Hironori Okabayashi, Kenichi Komada, Minoru Kidokoro, Tomomi Kitamura, Shinsuke Miyano, Tomoo Ito, Kongxay Phounphenghak, Chansay Pathammavong, Keiko Murano, Misato Nagai, Yoshio Mori, Katsuhiro Komase, Anonh Xeuatvongsa, Makoto Takeda, and Masahiko Hachiya

Subjects
Seroprevalence, Mumps, Pre-vaccination era, Nationwide cross-sectional population-based survey, Medicine, Biology (General), QH301-705.5, Science (General), Q1-390
Abstract

Abstract Objective Mumps-containing vaccine is currently not a component of the national immunization schedule in Lao People’s Democratic Republic (PDR). Mumps itself is not a notifiable disease in the country and the seroprevalence of anti-mumps immunoglobulin G (IgG) in the general population is unknown. In this study, anti-mumps IgG was measured in 2058 blood samples to evaluate population immunity in the country. Results The seroprevalence of anti-mumps IgG showed a gradual increase with increasing age, starting at 10.6% (95% CI 7.4–13.7) in participants aged 1–2 years, and almost plateaued at about 75% in individuals older than 11–12 years, though it still tended toward a small increase up to 89.6% (95% CI 86.6–92.6) in participants aged 40 years or older. Compared with the results of previous studies, this increase with increasing age is less marked and the plateau of anti-mumps seroprevalence is lower. We attribute this result mainly to the lower population density in Lao PDR.

Published
2019
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2. Seroprevalence of mumps before the introduction of mumps-containing vaccine in Lao PDR: results from a nationwide cross-sectional population-based survey

Author

Chansay Pathammavong, Shinsuke Miyano, Tomomi Kitamura, Hironori Okabayashi, Anonh Xeuatvongsa, Misato Nagai, Makoto Takeda, Minoru Kidokoro, Yoshio Mori, Masahiko Hachiya, Kongxay Phounphenghak, Kenichi Komada, Tomoo Ito, Keiko Murano, and Katsuhiro Komase

Subjects
0301 basic medicine, Male, lcsh:Medicine, Seroprevalence, Antibodies, Viral, Population density, 0302 clinical medicine, Seroepidemiologic Studies, Pre-vaccination era, Medicine, 030212 general & internal medicine, Child, lcsh:QH301-705.5, education.field_of_study, General Medicine, Middle Aged, Research Note, Mumps virus, Laos, Child, Preschool, Female, Adult, Adolescent, Notifiable disease, Population, Mumps Vaccine, Mass Vaccination, General Biochemistry, Genetics and Molecular Biology, Herd immunity, 03 medical and health sciences, Young Adult, Humans, lcsh:Science (General), education, Population based survey, Mumps, business.industry, lcsh:R, Infant, 030104 developmental biology, Cross-Sectional Studies, lcsh:Biology (General), Immunization, Immunoglobulin G, Nationwide cross-sectional population-based survey, Gradual increase, business, lcsh:Q1-390, Demography
Abstract

Objective Mumps-containing vaccine is currently not a component of the national immunization schedule in Lao People’s Democratic Republic (PDR). Mumps itself is not a notifiable disease in the country and the seroprevalence of anti-mumps immunoglobulin G (IgG) in the general population is unknown. In this study, anti-mumps IgG was measured in 2058 blood samples to evaluate population immunity in the country. Results The seroprevalence of anti-mumps IgG showed a gradual increase with increasing age, starting at 10.6% (95% CI 7.4–13.7) in participants aged 1–2 years, and almost plateaued at about 75% in individuals older than 11–12 years, though it still tended toward a small increase up to 89.6% (95% CI 86.6–92.6) in participants aged 40 years or older. Compared with the results of previous studies, this increase with increasing age is less marked and the plateau of anti-mumps seroprevalence is lower. We attribute this result mainly to the lower population density in Lao PDR.

Published
2019

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