Ed Anna C Mastroianni, Ruth Faden, Daniel Federman National Academy Press, £28 (vol 1), £23 (vol 2), pp 271 (vol 1), 247 (vol 2) ISBN 0-309-04992-X (vol 1), 0-309-05040-5 (vol 2) Ed Michael A Grodin, Leonard H Glantz Oxford University Press, pounds sterling 30, pp 258 ISBN 0-19-507103 A profound change has occurred in societal attitudes towards participation in medical research, but it has gone almost unnoticed. Some sections of the community are actually queuing up and indeed demanding to be included as research subjects in clinical studies. The favourite fantasy of clinical researchers seems to be coming true. What powerful forces have brought about this dramatic change in public perception of human experimentation? One major factor is the improved protection provided to research subjects from the legislative …