1. COVID-19-related diffuse leukoencephalopathy with microbleeds and persistent coma: a case report with good clinical outcome.
- Author
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Witvoet EH, Jiang FY, Laumans W, and de Bruijn SFTM
- Subjects
- Cerebral Hemorrhage chemically induced, Cerebral Hemorrhage diagnostic imaging, Coma chemically induced, Glasgow Coma Scale, Humans, Male, Middle Aged, SARS-CoV-2, COVID-19, Leukoencephalopathies diagnosis, Leukoencephalopathies diagnostic imaging
- Abstract
A 60-year-old patient presented with respiratory distress, after recently being tested COVID-19 positive and was mechanically ventilated for 15 days. After cessation of sedation, he remained in deep comatose state, without any reaction on pain stimuli (Glasgow Coma Score 3). MRI of the brain showed diffuse leukoencephalopathy and multiple (>50) microbleeds. Diffuse COVID-19-associated leukoencephalopathy with microhaemorrhages is associated with a poor prognosis. However, 3 months later, our patient showed a remarkable recovery and was able to walk independently. This case report shows COVID-related leukoencephalopathy and intracerebral microbleeds, even with persistent comatose state, may have a favourable clinical outcome and prolonged treatment should be considered in individual cases., Competing Interests: Competing interests: None declared., (© BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.)
- Published
- 2021
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