1. Risk of tuberculosis in patients with HIV-I and HIV-II infections in Abidjan, Ivory Coast.
- Author
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De Cock KM, Gnaore E, Adjorlolo G, Braun MM, Lafontaine MF, Yesso G, Bretton G, Coulibaly IM, Gershy-Damet GM, and Bretton R
- Subjects
- Adult, Blood Donors, Cote d'Ivoire, Cross-Sectional Studies, Female, HIV Infections epidemiology, Humans, Male, Middle Aged, Odds Ratio, Prevalence, Risk Factors, Tuberculosis, Pulmonary complications, HIV Infections complications, HIV-1, HIV-2, Tuberculosis complications
- Abstract
Objective: To examine the association between HIV-II infection and tuberculosis., Design: Cross sectional study comparing the prevalence of HIV-I and HIV-II infections in patients with tuberculosis and in blood donors., Setting: Abidjan, Ivory Coast, west Africa., Patients: 2043 consecutive ambulant patients with tuberculosis (confirmed pulmonary, presumed pulmonary, or extrapulmonary) and 2127 volunteer blood donors., Main Outcome Measure: Prevalence of HIV-I and HIV-II infections as assessed by presence of serum antibodies., Results: Overall rates of HIV infection were 40.2% in patients with tuberculosis (26.4% positive for HIV-I, 4.7% for HIV-II, and 9.0% for both); and 10.4% in blood donors (7.2% positive for HIV-I, 1.9% for HIV-II, and 1.3% for both). HIV-II infection was significantly more common in patients with all types of tuberculosis than in blood donors (97/2043, 4.7% v 40/2127, 1.9%; odds ratio 3.8%, 95% confidence interval 2.6 to 5.6)., Conclusion: Both HIV-I and HIV-II infections are associated with tuberculosis in Abidjan. 35% of adult tuberculosis in Abidjan is attributable to HIV infection and 4% specifically to HIV-II.
- Published
- 1991
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