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2 results on '"Yi minority"'

1. Prevalence of hepatitis C virus infection and its correlates in a rural area of southwestern China: a community-based cross-sectional study

Author

Peng-Lei Xiao, Jianchuan Gao, Song Liang, Qingwu Jiang, Wuli Yihuo, Xiu-Xia Song, Yue Chen, Wanting Cheng, Yan Shi, Ya Yang, and Yi-Biao Zhou

Subjects
hepatitis C virus, Male, Rural Population, Blood transfusion, Cross-sectional study, medicine.medical_treatment, HIV Infections, Hepacivirus, medicine.disease_cause, 0302 clinical medicine, Risk Factors, Ethnicity, 030212 general & internal medicine, Yi minority, drug abuse, education.field_of_study, Transmission (medicine), General Medicine, Middle Aged, Substance abuse, Infectious Diseases, Marital status, 030211 gastroenterology & hepatology, Female, Adult, medicine.medical_specialty, China, Adolescent, Hepatitis C virus, Population, 03 medical and health sciences, Young Adult, Age Distribution, Internal medicine, medicine, Humans, Sex Distribution, education, business.industry, Public health, Research, HIV, Hepatitis C Antibodies, Hepatitis C, Chronic, medicine.disease, Cross-Sectional Studies, Logistic Models, Immunology, business
Abstract

ObjectivesHepatitis C virus (HCV) infection is a major public health problem in southwestern China. Our aim of the study was to assess the prevalence of HCV infection and its correlates in the Yi population of this region.MethodsA community-based survey was conducted to investigate sociodemographic characteristics and other associated factors for HCV infection in a rural area of southwestern China. Blood samples were collected and tested for antibodies to HCV. Anti-HCV positive samples were further assessed for HCV RNA.ResultsA total of 2558 participants aged≥14 years were included in our analysis. Of them, 2.8% (95% CI 2.2% to 3.5%) were positive for HCV antibody. Multiple logistic regression analysis revealed that sex (male vs female: adjusted OR (aOR)=3.30, 95% CI 1.80 to 6.07), marital status (unmarried vs married: aOR=0.27, 95% CI 0.09 to 0.80), ever using injection drug (aOR=28.65, 95% CI 15.9 to 51.64) and ever having blood transfusion (aOR=7.64, 95% CI 1.94 to 30.16) were significantly associated with HCV infection (indicated by positive HCV antibody). Stratified analysis by HIV infection found that in HIV-negative individuals, sex (male vs female: aOR=3.84, 95% CI 1.88 to 7.85), ever using injection drug (aOR=22.15, 95% CI 8.45 to 58.04), having multiple sexual partners (aOR=2.57, 95% CI 1.26 to 5.23), and ever having blood transfusion (aOR=16.54, 95% CI 4.44 to 61.58) were significantly associated with HCV infection and in HIV-positive individuals, ever using injection drug (aOR=8.96, 95% CI 3.16 to 25.38) was associated with HCV infection.ConclusionThe data suggested a higher risk of HCV infection in this area when compared with the rest of China and some unique associated factors. Rapid scale-up of targeted interventions are needed to prevent further transmission and consequent morbidities.

Published
2017

2. Prevalence of hepatitis C virus infection and its correlates in a rural area of southwestern China: a community-based cross-sectional study.

Author

Cheng W, Yang Y, Zhou Y, Xiao P, Shi Y, Gao J, Chen Y, Liang S, Yihuo W, Song X, and Jiang Q

Subjects
Adolescent, Adult, Age Distribution, China epidemiology, Cross-Sectional Studies, Ethnicity, Female, Hepacivirus, Humans, Logistic Models, Male, Middle Aged, Risk Factors, Rural Population, Sex Distribution, Young Adult, HIV Infections complications, Hepatitis C Antibodies blood, Hepatitis C, Chronic ethnology
Abstract

Objectives: Hepatitis C virus (HCV) infection is a major public health problem in southwestern China. Our aim of the study was to assess the prevalence of HCV infection and its correlates in the Yi population of this region., Methods: A community-based survey was conducted to investigate sociodemographic characteristics and other associated factors for HCV infection in a rural area of southwestern China. Blood samples were collected and tested for antibodies to HCV. Anti-HCV positive samples were further assessed for HCV RNA., Results: A total of 2558 participants aged ≥ 14 years were included in our analysis. Of them, 2.8% (95% CI 2.2% to 3.5%) were positive for HCV antibody. Multiple logistic regression analysis revealed that sex (male vs female: adjusted OR (aOR)=3.30, 95% CI 1.80 to 6.07), marital status (unmarried vs married: aOR=0.27, 95% CI 0.09 to 0.80), ever using injection drug (aOR=28.65, 95% CI 15.9 to 51.64) and ever having blood transfusion (aOR=7.64, 95% CI 1.94 to 30.16) were significantly associated with HCV infection (indicated by positive HCV antibody). Stratified analysis by HIV infection found that in HIV-negative individuals, sex (male vs female: aOR=3.84, 95% CI 1.88 to 7.85), ever using injection drug (aOR=22.15, 95% CI 8.45 to 58.04), having multiple sexual partners (aOR=2.57, 95% CI 1.26 to 5.23), and ever having blood transfusion (aOR=16.54, 95% CI 4.44 to 61.58) were significantly associated with HCV infection and in HIV-positive individuals, ever using injection drug (aOR=8.96, 95% CI 3.16 to 25.38) was associated with HCV infection., Conclusion: The data suggested a higher risk of HCV infection in this area when compared with the rest of China and some unique associated factors. Rapid scale-up of targeted interventions are needed to prevent further transmission and consequent morbidities., Competing Interests: Competing interests: None declared., (© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.)

Published
2017
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