1. [Action of indoprofen on atrio-ventricular conduction. Preliminary note]
- Author
-
Caroli R, Pierfelice O, Roma F, Conte T, Palella M, Gaetano D'Ambrosio, Russo M, Milella M, and Ginevrino P
- Subjects
Male ,Phenylpropionates ,Heart Conduction System ,Palliative Care ,Atrioventricular Node ,Electric Conductivity ,Humans ,Coronary Disease ,Female ,Middle Aged ,Indoprofen ,Aged - Abstract
The purpose of the present study was to evaluate the possible electrophysiological effects of Indoprophene, a new non steroidal analgesic anti-inflammatory agent, which might be employed in the treatment of chest-pain from myocardial ischemia. Ten patient, who were undergoing a electrophysiological study for diagnostic purposes, were given 400 mg of indoprophene by intravenous rapid bolus. The A-V conduction times were recorded in basic condition and 30 minutes after administration of the drug. The data we collected show that Indoprophene does not influences either normal or prolonged A-V conduction times. We conclude that the drug, as it has a good effect on pain and lacks haemodynamic consequences and effects on conduction and excitability, is recommendable for the treatment of chest-pain from myocardial ischemia.
- Published
- 1984