1. The American Brachytherapy Society consensus guidelines for plaque brachytherapy of uveal melanoma and retinoblastoma
- Author
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Mark J. Rivard, Virpi Raivio, Walter Choi, Lars Hjelmqvist, John E. Mignano, Ekaterina Semenova, Santosh G Honavar, Stefan Seregard, E. Rand Simpson, Lorenzo Brualla, Chris S. Bergstrom, Marie Lundell, P. Mayles, Charlotta All-Eriksson, S.V. Saakyan, Normand Laperrierre, Holger Geischen, R Doug Errington, Anush Amiryan, Vladimir Valskiy, A. Mazal, Nina Kalach, Naoya Murakami, Rémi Dendale, Hans E. Grossniklaus, Shigenobu Suzuki, Göran Lundell, Laurence Desjardins, Pradeep Patra, Vijay Anand P. Reddy, Norbert Bornfeld, Matthew W. Wilson, Georges Sinclair, Bertil Damato, Wolfgang Sauerwein, Brenda L. Gallie, Ian R. Crocker, Jay S. Duker, Tero Kivelä, Barrett G. Haik, Akbar Beiki-Ardakani, Paul T. Finger, Elizabeth Butker, D. Fluehs, Jorma Heikkonen, and Helen Mayles
- Subjects
Uveal Neoplasms ,medicine.medical_specialty ,Consensus ,medicine.medical_treatment ,Retinal Neoplasms ,Brachytherapy ,Medizin ,Guidelines ,Subspecialty ,ABS ,medicine ,Methods ,Humans ,Radiology, Nuclear Medicine and imaging ,Medical physics ,Melanoma ,Plaque ,Radiation ,Retinoblastoma ,business.industry ,Plaque brachytherapy ,medicine.disease ,eye diseases ,United States ,Radiation therapy ,medicine.anatomical_structure ,Oncology ,Radiology Nuclear Medicine and imaging ,Practice Guidelines as Topic ,Choroid ,business ,Dose rate - Abstract
Purpose To present the American Brachytherapy Society (ABS) guidelines for plaque brachytherapy of choroidal melanoma and retinoblastoma. Methods and Materials An international multicenter Ophthalmic Oncology Task Force (OOTF) was assembled to include 47 radiation oncologists, medical physicists, and ophthalmic oncologists from 10 countries. The ABS-OOTF produced collaborative guidelines, based on their eye cancer–specific clinical experience and knowledge of the literature. This work was reviewed and approved by the ABS Board of Directors as well as within the journal's peer-reivew process. Results The ABS-OOTF reached consensus that ophthalmic plaque radiation therapy is best performed in subspecialty brachytherapy centers. Quality assurance, methods of plaque construction, and dosimetry should be consistent with the 2012 joint guidelines of the American Association of Physicists in Medicine and ABS. Implantation of plaque sources should be performed by subspecialty-trained surgeons. Although there exist select restrictions related to tumor size and location, the ABS-OOTF agreed that most melanomas of the iris, ciliary body, and choroid could be treated with plaque brachytherapy. The ABS-OOTF reached consensus that tumors with gross orbital extension and blind painful eyes and those with no light perception vision are unsuitable for brachytherapy. In contrast, only select retinoblastomas are eligible for plaque brachytherapy. Prescription doses, dose rates, treatment durations, and clinical methods are described. Conclusions Plaque brachytherapy is an effective eye and vision-sparing method to treat patients with intraocular tumors. Practitioners are encouraged to use ABS-OOTF guidelines to enhance their practice.
- Published
- 2013