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Your search keyword '"MESH: Brain Mapping"' showing total 3 results
Start Over Descriptor "MESH: Brain Mapping" Journal brain research
3 results on '"MESH: Brain Mapping"'

1. Reading sadness beyond human faces

Author

Stéphanie Dubal, Jacqueline Nadel, Mariam Chammat, Aurélie Foucher, Vulnérabilité Adaptation et Psychopathologie (VAP), Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS), Centre Emotion, Université Pierre et Marie Curie - Paris 6 (UPMC)-CHU Pitié-Salpêtrière [AP-HP], Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS), CHU Pitié-Salpêtrière [AP-HP], and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Centre National de la Recherche Scientifique (CNRS)

Subjects
Male, MESH: Evoked Potentials, Visual, MESH: Facial Expression, Emotions, 0302 clinical medicine, Reading (process), MESH: Brain Mapping, media_common, Brain Mapping, General Neuroscience, 05 social sciences, Cognition, Electroencephalography, Sadness, Facial Expression, MESH: Photic Stimulation, Pattern Recognition, Visual, MESH: Young Adult, Facilitation, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Female, Psychology, MESH: Face, Cognitive psychology, Adolescent, media_common.quotation_subject, MESH: Pattern Recognition, Visual, MESH: Reading, behavioral disciplines and activities, 050105 experimental psychology, 03 medical and health sciences, Young Adult, Perception, MESH: Electroencephalography, Reaction Time, Humans, 0501 psychology and cognitive sciences, Molecular Biology, MESH: Emotions, MESH: Adolescent, Communication, MESH: Humans, business.industry, Inversion (music), MESH: Male, MESH: Reaction Time, body regions, Electrophysiology, Reading, Face, Evoked Potentials, Visual, Neurology (clinical), business, MESH: Female, 030217 neurology & neurosurgery, Photic Stimulation, Developmental Biology
Abstract

International audience; Human faces are the main emotion displayers. Knowing that emotional compared to neutral stimuli elicit enlarged ERPs components at the perceptual level, one may wonder whether this has led to an emotional facilitation bias toward human faces. To contribute to this question, we measured the P1 and N170 components of the ERPs elicited by human facial compared to artificial stimuli, namely non-humanoid robots. Fifteen healthy young adults were shown sad and neutral, upright and inverted expressions of human versus robotic displays. An increase in P1 amplitude in response to sad displays compared to neutral ones evidenced an early perceptual amplification for sadness information. P1 and N170 latencies were delayed in response to robotic stimuli compared to human ones, while N170 amplitude was not affected by media. Inverted human stimuli elicited a longer latency of P1 and a larger N170 amplitude while inverted robotic stimuli did not. As a whole, our results show that emotion facilitation is not biased to human faces but rather extend to non-human displays, thus suggesting our capacity to read emotion beyond faces.

Published
2009
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2. Specific regional distribution of gec1 mRNAs in adult rat central nervous system

Author

Fabrice Tolle, Michaël Boyer-Guittaut, Emilie Rossi, Pierre Yves Risold, Michèle Jouvenot, Virginie Mansuy-Schlick, Annick Fraichard, Laboratoire d'Histologie, embryologie et cytogénétique, Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), and Estrogènes, Expression génique et pathologies du Système Nerveux Central - UFC (E2SNC / ESTROGENES)

Subjects
Male, Cerebellum, MESH: Neurons, MESH: Rats, Sprague-Dawley, MESH: Spinal Cord, Rats, Sprague-Dawley, 0302 clinical medicine, GABA receptor, Neural Pathways, MESH: Animals, MESH: Receptors, GABA-A, MESH: Brain Mapping, In Situ Hybridization, Neurons, 0303 health sciences, Brain Mapping, Cerebrum, General Neuroscience, Brain, medicine.anatomical_structure, Spinal Cord, Brainstem, Microtubule-Associated Proteins, MESH: Rats, GABARAP, Central nervous system, MESH: Carrier Proteins, In situ hybridization, Biology, 03 medical and health sciences, MESH: Brain, MESH: In Situ Hybridization, medicine, Animals, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, Northern blot, RNA, Messenger, Molecular Biology, 030304 developmental biology, MESH: Adaptor Proteins, Signal Transducing, MESH: RNA, Messenger, Adaptor Proteins, Signal Transducing, MESH: Neural Pathways, Receptors, GABA-A, Molecular biology, MESH: Antisense Elements (Genetics), MESH: Male, Rats, MESH: Microtubule-Associated Proteins, Antisense Elements (Genetics), Neurology (clinical), Carrier Proteins, 030217 neurology & neurosurgery, Developmental Biology
Abstract

International audience; GEC1 protein shares high identity with GABARAP (GABA(A) Receptor-Associated Protein), interacts with tubulin and GABA(A) receptors and is potentially involved in intracellular transport processes. Recently, using quantitative real time PCR, we have reported the gec1 mRNA expression in different rat brain areas. In the present study, we investigated the cell types expressing gec1 in rat brain. Sense and anti-sense gec1 RNA probes, corresponding to the 3'-untranslated region, were generated. In northern blotting experiments, the anti-sense probe revealed only the 1.75 kb gec1 mRNAs. On the other hand, in immunohistochemistry experiments, GEC1 polyclonal antibodies did not discriminate between GEC1 and GABARAP proteins. Therefore, we used digoxigenin-labeled RNA probes for in situ hybridization (ISH) experiments to map the gec1 expression. Using the anti-sense probe, we detected the gec1 mRNAs specifically in neurons throughout the rostrocaudal extent of the brain as well as in the spinal cord. Although a majority of neurons expressed the gec1 mRNAs, different intensities of labeling were observed depending on the areas: the strongest labeling was observed in the isocortex, hippocampus, basal telencephalon, some thalamic and most of hypothalamic nuclei, cerebellum, and numerous brainstem nuclei. Furthermore, the gec1 mRNAs were intensely expressed in neurons involved in somatomotor and neuroendocrine functions and weakly expressed in sensory and reticular structures. These results corroborate the putative role of the GEC1 protein in the trafficking of receptor GABA(A).

Published
2007
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3. Altered cerebral glucose metabolism in an animal model of diabetes insipidus: a micro-PET study

Author

Arlette Burlet, Sophie Paris, Maria-Joao Ribeiro, Homa Adle-Biassette, Christine Coulon, Ahmed Idbaih, Jean Donadieu, Khê Hoang-Xuan, Yannick Marie, Raphaël Boisgard, Service de neurologie 1 [CHU Pitié-Salpétrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Biologie des Interactions Neurones / Glie, Université Pierre et Marie Curie - Paris 6 (UPMC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Systèmes Neuromodulateurs des Comportements Ingestifs, Génétique et Développements (EA 3453), Nancy Université, Service d'Anatomie et cytologie pathologique, Université Paris Diderot - Paris 7 (UPD7)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Service Hospitalier Frédéric Joliot (SHFJ), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay, Service d'hématologie-immunologie-oncologie pédiatrique [CHU Trousseau], Université Pierre et Marie Curie - Paris 6 (UPMC)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-CHU Trousseau [APHP], Idbaih, Ahmed, Service de Neurologie [CHU Pitié-Salpêtrière], IFR70-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-AP-HP - Hôpital Bichat - Claude Bernard [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Université Paris Diderot - Paris 7 (UPD7), Université Paris-Saclay-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), CHU Trousseau [APHP], and Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)

Subjects
Glucose uptake, 0302 clinical medicine, MESH: Fluorodeoxyglucose F18, MESH: Rats, Brattleboro, MESH: Animals, MESH: Brain Mapping, [SDV.MHEP.EM] Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, Cerebral Cortex, 0303 health sciences, Brain Mapping, biology, General Neuroscience, Rats, Brattleboro, [SDV.MHEP.EM]Life Sciences [q-bio]/Human health and pathology/Endocrinology and metabolism, MESH: Positron-Emission Tomography, MESH: Glucose, medicine.anatomical_structure, Cerebral cortex, MESH: Diabetes Insipidus, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], MESH: Radiopharmaceuticals, hormones, hormone substitutes, and hormone antagonists, medicine.medical_specialty, MESH: Rats, Central nervous system, 03 medical and health sciences, MESH: Rats, Long-Evans, In vivo, Fluorodeoxyglucose F18, MESH: Analysis of Variance, Diabetes mellitus, Internal medicine, medicine, Animals, Rats, Long-Evans, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Molecular Biology, 030304 developmental biology, Analysis of Variance, business.industry, medicine.disease, biology.organism_classification, MESH: Cerebral Cortex, Brattleboro rat, Rats, [SDV.AEN] Life Sciences [q-bio]/Food and Nutrition, Disease Models, Animal, Endocrinology, Glucose, Positron-Emission Tomography, Diabetes insipidus, Neurology (clinical), MESH: Disease Models, Animal, Radiopharmaceuticals, business, [SDV.AEN]Life Sciences [q-bio]/Food and Nutrition, 030217 neurology & neurosurgery, Ex vivo, Diabetes Insipidus, Developmental Biology
Abstract

International audience; The Brattleboro rat is an animal model of genetically induced central diabetes insipidus. These rats show cognitive and behavioral disorders, but no neurodegenerative disease has been observed. We studied brain glucose uptake, a marker of neuronal activity, in 6 Brattleboro rats, in comparison with 6 matched Long-Evans (LE) control rats. A group of 3 Brattleboro rats and 3 Long-Evans rats was studied in vivo and another group of animals was studied ex vivo. In vivo studies were performed using fluorodeoxyglucose labeled with fluorine 18 ((18)F-FDG) and a dedicated small-animal PET device. At 30 min and 60 min p.i., (18)F-FDG uptake was significantly higher in the frontal cortex, striatum, thalamus and cerebellum of Brattleboro rats than in LE rats when measured by PET in vivo (p

Published
2007
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