1. First reported case of Gilbertella persicaria in human stool: outcome of a community study from Segamat, Johor, Malaysia
- Author
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Daniel D. Reidpath, Joash Ban Lee Tan, Sadequr Rahman, Marie Andrea Laetitia Huët, Jacky Dwiyanto, Calvin Bok Sun Goh, Sui Mae Lee, Kuan Shion Ong, and Li Wen Wong
- Subjects
Mucorales ,Male ,Veterinary medicine ,Adolescent ,Fungus ,Microbiology ,03 medical and health sciences ,Feces ,Microbial ecology ,Mycology ,Media Technology ,Food microbiology ,Humans ,030304 developmental biology ,0303 health sciences ,biology ,Calcium Oxalate ,030306 microbiology ,Hydrogen-Ion Concentration ,Isolation (microbiology) ,biology.organism_classification ,Urease ,Anti-Bacterial Agents ,Gastrointestinal Microbiome ,Fungal and Bacterial Physiology - Short Communication ,Biofilms ,Carrier State ,Genome, Fungal ,Gilbertella persicaria - Abstract
Species of fungi belonging to the order Mucorales can be found everywhere in the environment. Gilbertella persicaria, which belongs to this order, have often been isolated from fruits and in water systems. However, there has been no report of isolation of this fungus from human samples. During a gut mycobiome study, from the Segamat community, Gilbertella persicaria was isolated from a human fecal sample and was characterized through a series of morphological assessment, biochemical tests, and molecular techniques. The isolate produced a white velvety surface that turned grayish after 24 h. Although no biofilm production was observed, the results indicated that the isolate could form calcium oxalate crystals, produced urease, and was resistant to low pH. The isolate was sensitive to amphotericin but resistant to voriconazole and itraconazole. The features of this fungus that could help in its survival in the human gut are also discussed. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s42770-020-00323-z) contains supplementary material, which is available to authorized users.
- Published
- 2020