1. Extramedullary plasmacytoma of the breast with serum igd monoclonal protein: a case report and review of the literature
- Author
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Koji Ogawa, Hiroyuki Yamaoka, Takashi Ishikawa, Akira Ishiyama, Toshiro Kouno, Yukio Nakatani, Nobuyoshi Momiyama, Akira Kubo, Hiroshi Shimada, Hitoshi Kitamura, Takako Doi, and Atsushi Takimoto
- Subjects
Vincristine ,Pathology ,medicine.medical_specialty ,biology ,Cyclophosphamide ,business.industry ,medicine.medical_treatment ,General Medicine ,medicine.disease ,Immunoglobulin D ,medicine.anatomical_structure ,Breast cancer ,Oncology ,biology.protein ,medicine ,Plasmacytoma ,Pharmacology (medical) ,Radiology, Nuclear Medicine and imaging ,Bone marrow ,skin and connective tissue diseases ,business ,Mastectomy ,Multiple myeloma ,medicine.drug - Abstract
A case of extramedullary plasmacytoma (EMP) of the breast in a 49-year-old woman is reported. Six cases of EMP of the breast have been previously reported in the world literature, but this case is unusual in that it was associated with serum IgD lamda monoclonal protein detected by serum immunoelectrophoresis. The protein was identical to the immunoprotein found in proliferating cells of the breast. Bone marrow aspiration revealed normal plasma cells indicating that the breast tumor did not represent extramedullary involvement of multiple myeloma or myelomatosis. An associated tumor was found in the nasal cavity after local treatment (mastectomy) of the breast tumor, but the patient remained disease-free 12 months after adjuvant chemotherapy using nidlan, natulan, alkelan, prednisone, cyclophosphamide and vincristine.
- Published
- 1999
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