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Your search keyword '"Gildo, Matta"' showing total 2 results
Start Over Author "Gildo, Matta" Journal british journal of haematology
2 results on '"Gildo, Matta"'

1. Glutathione S-transferase gene polymorphism and cardiac iron overload in thalassaemia major

Author

Stefania Satta, Gildo Matta, Renzo Galanello, and Raffaella Origa

Subjects
Adult, Genetic Markers, Iron Overload, Polymorphism, Genetic, Thalassaemia major, biology, business.industry, beta-Thalassemia, Hematology, Molecular biology, Glutathione S-transferase, Ferritins, biology.protein, Cardiac iron, Humans, Medicine, Gene polymorphism, Cardiomyopathies, business, Glutathione Transferase
Published
2008
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2. Impact of heart magnetic resonance imaging on chelation choices, compliance with treatment and risk of heart disease in patients with thalassaemia major

Author

Renzo Galanello, Raffaella Origa, Gildo Matta, Carlo Dessì, GiovanBattista Leoni, Patrizio Bina, Maddalena Morittu, Fabrice Danjou, S. Cossa, Elisabetta Defraia, and Maria Loreta Foschini

Subjects
Adult, Male, Risk, medicine.medical_specialty, Iron Overload, Heart disease, Pyridones, Iron, Deferoxamine, Iron Chelating Agents, Benzoates, Sampling Studies, Young Adult, Predictive Value of Tests, Internal medicine, Medicine, Humans, In patient, Deferiprone, Patient compliance, Heart Failure, medicine.diagnostic_test, Thalassaemia major, Dose-Response Relationship, Drug, business.industry, Myocardium, beta-Thalassemia, Transfusion Reaction, Magnetic resonance imaging, Arrhythmias, Cardiac, Hematology, Triazoles, medicine.disease, Magnetic Resonance Imaging, Chelation Therapy, Compliance (physiology), Deferasirox, ROC Curve, Heart failure, Area Under Curve, Cohort, Cardiology, Patient Compliance, Drug Therapy, Combination, Female, business
Abstract

Summary This study aimed to verify the impact of heart magnetic resonance imaging on chelation choices and patient compliance in a single-institution cohort as well as its predictive value for heart failure and arrhythmias. Abnormal cardiac T2* values determined changes in treatment in most subjects. Heart T2* was confirmed to be highly predictive over 1 year for heart failure and arrhythmias. The choice of chelation regimens known to remove heart iron efficiently was not sufficient by itself to influence the risk. Compliance with treatment had a more remarkable role.

Published
2013

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