1. Salivary immunoglobulin A response at rest and after exercise following a 48 h period of fluid and/or energy restriction
- Author
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Sally Wilson, Robert Walters, Stewart J. Laing, Samuel J. Oliver, Neil P. Walsh, and James L. J. Bilzon
- Subjects
Adult ,Blood Glucose ,Male ,Immunoglobulin A ,medicine.medical_specialty ,Saliva ,Hydrocortisone ,Drinking ,Medicine (miscellaneous) ,Physical exercise ,Fatty Acids, Nonesterified ,Energy requirement ,Specimen Handling ,Time trial ,Internal medicine ,medicine ,Humans ,Plasma Volume ,Exercise physiology ,Exercise ,Salivary immunoglobulin A ,Nutrition and Dietetics ,Water Deprivation ,biology ,Chemistry ,Diet ,Endocrinology ,Immunoglobulin A, Secretory ,biology.protein ,Fluid restriction ,Energy Intake ,Food Deprivation ,Salivation - Abstract
The aim was to investigate the effects of a 48 h period of fluid, energy or combined fluid and energy restriction on salivary IgA (s-IgA) responses at rest and after exercise. Thirteen healthy males (age 21 (sem1) years) participated in four randomised 48 h trials. In the control trial participants received their estimated energy (12 154 (sem230) kJ/d) and water (3912 (sem140) ml/d) requirements. On fluid restriction (FR) participants received their energy requirements and 193 (sem19) ml water/d to drink and on energy restriction (ER) participants received their water requirements and 1214 (sem25) kJ/d. Fluid and energy restriction (F+ER) was a combination of FR and ER. After 48 h, participants performed a 30 min treadmill time trial (TT) followed by rehydration (0–2 h) and refeeding (2–6 h). Unstimulated saliva was collected at 0, 24 and 48 h, post-TT, and 2 and 6 h post-TT. Saliva flow rate (sflw) and s-IgA (ELISA) remained unchanged in control conditions and on ER. However, 48 h on FR decreased sflw (64 %) which most probably accounted for the increase in s-IgA concentration (P sem2); 24 h: 12 (sem2) μg/min;P
- Published
- 2007
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