1. Influence of childhood trauma on diagnosis and substance use in first-episode psychosis.
- Author
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Tomassi, S., Tosato, S., Mondelli, V., Faravelli, C., Lasalvia, A., Fioravanti, G., Bonetto, C., Fioritti, A., Cremonese, C., Lo Parrino, R., De Santi, K., Meneghelli, A., Torresani, S., De Girolamo, G., Semrov, E., Pratelli, M., Cristofalo, D., Ruggeri, M., and GET UP Group
- Subjects
TRAUMATIC psychoses ,EMOTIONAL trauma in children ,SUBSTANCE abuse & psychology ,AFFECTIVE disorders ,COCAINE abuse ,HEROIN abuse ,PHYSICAL abuse ,CHILD sexual abuse & psychology - Abstract
BackgroundChildhood trauma has been significantly associated with first-episode psychosis, affective dysfunction and substance use.AimsTo test whether people with first-episode psychosis who had experienced childhood trauma, when compared with those who had not, showed a higher rate of affective psychosis and an increased lifetime rate of substance use.MethodThe sample comprised 345 participants with first-episode psychosis (58% male, mean age 29.8 years, s.d. = 9.7).ResultsSevere sexual abuse was significantly associated with a diagnosis of affective psychosis (χ2 = 4.9, P = 0.04) and with higher rates of lifetime use of cannabis (68% v 41%; P = 0.02) and heroin (20% v 5%; P = 0.02). Severe physical abuse was associated with increased lifetime use of heroin (15% v 5%; P = 0.03) and cocaine (32% v 17%; P = 0.05).ConclusionsPatients with first-episode psychosis exposed to childhood trauma appear to constitute a distinctive subgroup in terms of diagnosis and lifetime substance use. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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