1. [Disseminated intravascular coagulation in solid tumours].
- Author
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Ferrand FR, Garcia-Hejl C, Moussaid Y, Schernberg A, Bidard FC, Pavic M, Khenifer S, and Stoclin A
- Subjects
- Anticoagulants therapeutic use, Blood Coagulation physiology, Coagulants therapeutic use, Factor VIIa therapeutic use, Humans, Neoplasms pathology, Neoplasms therapy, Platelet Transfusion, Prognosis, Recombinant Proteins therapeutic use, Risk Factors, Disseminated Intravascular Coagulation blood, Disseminated Intravascular Coagulation diagnosis, Disseminated Intravascular Coagulation epidemiology, Disseminated Intravascular Coagulation etiology, Disseminated Intravascular Coagulation physiopathology, Disseminated Intravascular Coagulation therapy, Neoplasms blood, Paraneoplastic Syndromes blood, Paraneoplastic Syndromes diagnosis, Paraneoplastic Syndromes etiology, Paraneoplastic Syndromes physiopathology, Paraneoplastic Syndromes therapy
- Abstract
Disseminated intravascular coagulation (DIC) is a complex abnormality of hemostasis with dramatic consequences and long described as associated with tumors. Yet the diagnosis and management of paraneoplastic DIC are poorly defined. The purpose of this paper is to review DIC associated with solid tumors, at the pathophysiological and therapeutic levels in particular. We also report data from a recent retrospective series of patients with DIC in the context of a solid tumor, to illustrate the epidemiological, clinical and prognostic.
- Published
- 2014
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