1. [Results of postoperative cervical node irradiation in carcinoma of the pharyngo-larynx. A study of the cooperative group of radiotherapists].
- Author
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Hoffstetter S, Malissard L, N'Guyen TD, Panis X, Jung GM, Bachaud JM, Prevost B, Quint R, Chaplain G, Eschwège F, Rambert P, and Fleury-Touzeau F
- Subjects
- Actuarial Analysis, Adult, Aged, Carcinoma, Squamous Cell pathology, Carcinoma, Squamous Cell surgery, Combined Modality Therapy, Female, Humans, Laryngeal Neoplasms pathology, Laryngeal Neoplasms surgery, Lymphatic Metastasis, Male, Middle Aged, Neck, Pharyngeal Neoplasms pathology, Pharyngeal Neoplasms surgery, Postoperative Period, Radiotherapy Dosage, Retrospective Studies, Survival Analysis, Carcinoma, Squamous Cell radiotherapy, Laryngeal Neoplasms radiotherapy, Lymphatic Irradiation, Pharyngeal Neoplasms radiotherapy
- Abstract
From 1981 to 1985, 428 patients presenting with an epidermoid carcinoma of the hypopharynx and/or larynx were treated with a curative intent by surgical resection and postoperative irradiation. Two-thirds of the tumours were T3 and 60% of patients presented with a clinical node involvement. The rates of local failure were 8%, 18% and 13%, respectively, for cancers of the larynx, of the piriform sinus and of the posterior wall; the rates of regional failure were 8%, 23% and 13%, respectively. There is no head and neck site with either a high or low risk of recurrence after resection, but the capsular rupture remains a factor of poor prognosis. The survival rate at 5 years of the whole series is 38%, for laryngeal localisation it reaches 62%. The risk of metastases is related to the node involvement and the interval between surgery and irradiation.
- Published
- 1996