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Start Over Author "Dzyuman AN" Journal bulletin of experimental biology and medicine
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3. Airway Smooth Muscles Contractions in Metabolic Syndrome

Author

Yu G, Birulina, V V, Ivanov, E E, Buiko, A N, Dzyuman, A V, Nosarev, O V, Voronkova, M O, Vol'khina, and S V, Gusakova

Subjects
Bronchoconstrictor Agents, Metabolic Syndrome, Carbohydrates, Animals, Albuterol, Bronchi, Carbachol, Muscle, Smooth, Receptors, Cholinergic, Muscle Contraction, Rats
Abstract

We studied contractile responses of isolated airway smooth muscle segments from rats with metabolic syndrome. Metabolic syndrome was induced in rats by high-fat and high-carbohydrate diet. It was shown that metabolic syndrome was associated with an increase of bronchoconstrictor action of cholinergic receptor activator carbacholine (0.1-100 μM) and a decrease of the dilatory effect of β

Published
2022

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