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Start Over Author "Coutinho, Francisco" Journal bulletin of mathematical biology
6 results on '"Coutinho, Francisco"'

1. Estimating the Size of the HCV Infection Prevalence: A Modeling Approach Using the Incidence of Cases Reported to an Official Notification System

Author

Amaku, Marcos, primary, Burattini, Marcelo Nascimento, additional, Coutinho, Francisco Antonio Bezerra, additional, Lopez, Luis Fernandez, additional, Mesquita, Fabio, additional, Naveira, Marcelo Contardo Moscoso, additional, Pereira, Gerson Fernando Mendes, additional, Santos, Melina Érica, additional, and Massad, Eduardo, additional

Published
2016
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6. The Impact of Hepatitis A Virus Infection on Hepatitis C Virus Infection: A Competitive Exclusion Hypothesis.

Author

Amaku, Marcos, Coutinho, Francisco, Chaib, Eleazar, and Massad, Eduardo

Subjects
*HEPATITIS A virus, *HEPATITIS C virus, *VIRUS diseases, *IMMUNE system, *MATHEMATICAL models, *COMPETITIVE exclusion (Microbiology)
Abstract

We address the observation that, in some cases, patients infected with the hepatitis C virus (HCV) are cleared of HCV when super-infected with the hepatitis A virus (HAV). We hypothesise that this phenomenon can be explained by the competitive exclusion principle, including the action of the immune system, and show that the inclusion of the immune system explains both the elimination of one virus and the co-existence of both infections for a certain range of parameters. We discuss the potential clinical implications of our findings. [ABSTRACT FROM AUTHOR]

Published
2013
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