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1 results on '"*CELL imaging"'

1. A Quinoline-thiooxorhodamine Conjugate for Fluorescent Hg2+ Recognition in Aqueous Media and Living Cells.

Author

Lijun Tang, Xin Wen, Xin Dai, Di Wu, and Zhenlong Huang

Subjects
*FLUORESCENCE, *RHODAMINES, *CELL imaging, *STOICHIOMETRY, *CHEMICAL detectors
Abstract

A quinoline-thiooxorhodamine conjugate fluorescent sensor (1) has been synthesized. Sensor 1 exhibits high selectivity and sensitivity to Hg2+ in H2O/DMSO (95/5, v/v, HEPES 20 mM, pH = 7.4) solution with fluorescence detection. Other tested metal ions do not induce any significant fluorescence intensity changes. Sensor 1 interacts with Hg2+ through a 1:1 binding stoichiometry with a good anti-inference ability. In addition, fluorescent imaging of Hg2+ in Hela cells is also successfully demonstrated. [ABSTRACT FROM AUTHOR]

Published
2014
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