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Your search keyword '"Fumihiko Nakayama"' showing total 2 results
Start Over Author "Fumihiko Nakayama" Journal bunseki kagaku
2 results on '"Fumihiko Nakayama"'

1. Study on vitamin A reference standard for high performance liquid chromatography II: Formulation of retinyl acetate soft capsule and evaluation of its quality and stability

Author

Toshikazu TABATA, Kimihiko TAKADA, Yoshiaki ITO, Yukio SHOJI, Kei SAITO, Yasuji TAKASHIMA, Reijiro KOHNO, Hitoshi EZAWA, Etuko IWASAKI, Keiko SANTO, Yuko NOBE, Fumihiko NAKAYAMA, Yoritaka ORIMO, Yuji OHSAWA, Emiko OKAZAKI, Michiko NISHIKAWA, and Takao INOUE

Subjects
Analytical Chemistry
Published
1994
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2. Study on vitamin A reference standard for high performance liquid chromatography. Formulation of retinyl palmitate soft capsule and evaluation of its quality and stability

Author

Yukio Shoji, Toshikazu Tabata, Yoritaka Orimo, Yuji Ohsawa, Hitoshi Ezawa, Yuko Nobe, Etuko Iwasaki, Michiko Nishikawa, Keiko Santo, Yoshiaki Ito, Emiko Okazaki, Takao Inoue, Kimihiko Takada, Reijiro Kohno, Yasuji Takashima, Kei Saito, and Fumihiko Nakayama

Subjects
Vitamin, chemistry.chemical_compound, Chromatography, chemistry, Capsule, Retinyl acetate, Reference standards, High-performance liquid chromatography, Analytical Chemistry
Abstract

現在ビタミンAの定量には,高速液体クロマトグラフィー(HPLC)が広く用いられている.しかしHPLC用の標準品は,公共機関よりの交付がなされていない.そこでその標品を得るため「日局十」規格適合品のパルミチン酸レチノール{170万国際単位(IU)/g}を中鎖脂肪酸トリグリセライド(MCT)で20万IU/gに希釈し,ゼラチン軟カプセルとした.この試作標品について,それぞれ薄層クロマトグラフィー,紫外吸収スペクトル法及び一部HPLCにより12の実験室が参加して試験を行った.又安定性試験は,この標品について50℃,40℃,25℃及び室温で,6か月にわたり行ったが,その安定性は,期待以上の良好な結果を得ることができた.

Published
1986
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