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This study assesses the efficiency of the galactosemia add-on test in neonatal screening performed on regular Guthrie card blood spots. Based on estimated average incidence of galactosemia (1:19,984 newborns) in São Paulo State, Brazil, the study develops a cost-benefit analysis model, using a B/C ratio and a 9.25% annual interest rate in order to decapitalize the results. Sensitivity analysis is also performed, varying (as a function of the interest or discount rate) from 0 and 20% and according to the 95% confidence interval (1:7,494-1:59,953 newborns). The results show that the savings obtained by improved health of galactosemic patients detected early by add-on neonatal screening is superior to the costs (B/C=1.33), characterizing galactosemia add-on testing in neonatal screening as an efficient policy. The lower the prevailing interest rate in the economy, the more efficient the neonatal screening policy.

This article presents some results from a study aimed at analyzing the limits and possibilities defined by inter-subjective and unconscious processes of solidarity, cooperation, and life care production in health services. A public hospital with an emergency department in the city of Rio de Janeiro, Brazil, was selected as a case study. The French school of psychosociology, oriented by the psychoanalytical clinical approach, the psychoanalytical theory on inter-subjective and group processes, and work psychodynamics provided the basis for the study's methodological strategies and analysis of the results. The study analyzed health professionals' psychological representations and unconscious processes related to emergency department users and their demands, and their consequences for the health care provided to this clientele. Some particularly important images such as "need" were used as a category that conceals the diversity of demand, in an unconscious process with multiple reductions: from denial of social suffering to denial of the patients' human condition.

The clinical and diagnostic aspects of cystic fibrosis have been extensively reviewed, with an emphasis on neonatal screening. This systematic literature review involved a search for relevant contributions in the PubMed and SciELO databases. The first references to cystic fibrosis date to the Middle Ages. Cystic fibrosis is the most frequent autosomal recessive hereditary disease among Caucasians (1:2,000 to 3,500). More than 1,000 mutations lead to the disease, the most common being "F508, with 70% prevalence among Canadian, Northern European, and American Caucasians and 23 to 55% prevalence among Brazilians. The basic defect is in chloride ion secretion. Cystic fibrosis screening has long been controversial, and after almost three decades, there are few nationwide programs (most are regional or local). However, the U.S. Centers for Disease Control and Prevention (CDC) has concluded that screening for cystic fibrosis is justified. The lack of a specific screening test and the ethnic heterogeneity of the Brazilian population pose challenges for neonatal screening.

This article discusses management practices in public hospitals (general hospitals with emergency services) in the city of Rio de Janeiro, Brazil, based on a psychosociological approach to organizational analysis. Of the 12 existing hospitals, 8 were included in the current study, conducted from July 2003 to April 2004. The research, drawing on hospital directors' narratives, identified three management models. The first focuses on processes of change, highlighting symbolic and imaginative elements for building a vision of the future for the hospitals. The second concentrates on specific projects, which absorbs all the management efforts. A third pattern (predominant in the study) is marked by the struggle to keep the hospital working, with the image of urgency as the driving force. The imposition of continuous action leaves no room for reflection. The crisis in Rio de Janeiro's public hospitals has led to a "wartime" environment and thus the dissemination of the urgency-based model.

This article discusses the development of mental health care services based on the Anti-Asylum Movement. Drawing on contributions from psychoanalysis and social psychology, the study analyzes the conflicts and dilemmas arising in a Psychosocial Care Center (NAPS) in Santos, São Paulo, Brazil. This study is part of Master's degree research at the Social and Occupational Psychology Department, Institute of Psychology, University of São Paulo. Semi-structured interviews were used with workers at the NAPS. According to the interviews, the transformation of the mental health care model mobilizes psychological issues among the workers. Various conflicts and anxieties were observed in relation to changes in the institutional support provided by the NAPS over time. The article analyzes difficulties in dealing with differences in the team or feelings of abandonment resulting from changes in the local administration in the interface between subjects and the institution.

This study aimed to evaluate the operative group as a preventive approach among men who have sex with men that use two public health services in the city of São Paulo, Brazil. One hundred volunteers were randomly allocated to two groups (intervention and control, with 50 each). All participants answered questionnaires in two phases: before the intervention and six months after its conclusion. Effect was measured by comparing the groups for the following outcomes: median number of anal sex acts without condoms and responses from the participants to questions about HIV infection. 69 participants completed the study (34 in the prevention group and 35 in the control group). Analysis showed a decrease in the number of unprotected anal sex acts (p = 0.029) and an increase in the number of answers favoring prevention in the intervention group. The results indicate that the study group was responsive to a safer sex operative group intervention. Further research is necessary to evaluate the feasibility of this prevention approach as a public health strategy, including other social groups.