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7 results on '"Schiavon, Marco"'

1. Lung Transplantation in Patients with Previous or Unknown Oncological Disease: Evaluation of Short- and Long-Term Outcomes

Author

Catelli, Chiara, primary, Faccioli, Eleonora, additional, Silvestrin, Stefano, additional, Lorenzoni, Giulia, additional, Luzzi, Luca, additional, Bennett, David, additional, Schiavon, Marco, additional, Campisi, Alessio, additional, Bargagli, Elena, additional, Dell’Amore, Andrea, additional, and Rea, Federico, additional

Published
2024
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2. Microscopical Variables and Tumor Inflammatory Microenvironment Do Not Modify Survival or Recurrence in Stage I-IIA Lung Adenocarcinomas

Author

Dell’Amore, Andrea, primary, Bonis, Alessandro, additional, Melan, Luca, additional, Silvestrin, Stefano, additional, Cannone, Giorgio, additional, Shamshoum, Fares, additional, Zampieri, Alberto, additional, Pezzuto, Federica, additional, Calabrese, Fiorella, additional, Nicotra, Samuele, additional, Schiavon, Marco, additional, Faccioli, Eleonora, additional, Mammana, Marco, additional, Comacchio, Giovanni Maria, additional, Pasello, Giulia, additional, and Rea, Federico, additional

Published
2023
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3. Precision Surgery in NSCLC

Author

Cannone, Giorgio, primary, Comacchio, Giovanni Maria, additional, Pasello, Giulia, additional, Faccioli, Eleonora, additional, Schiavon, Marco, additional, Dell’Amore, Andrea, additional, Mammana, Marco, additional, and Rea, Federico, additional

Published
2023
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4. The Multidisciplinary Approach in Stage III Non-Small Cell Lung Cancer over Ten Years: From Radiation Therapy Optimisation to Innovative Systemic Treatments

Author

Ferro, Alessandra, primary, Sepulcri, Matteo, additional, Schiavon, Marco, additional, Scagliori, Elena, additional, Mancin, Edoardo, additional, Lunardi, Francesca, additional, Gennaro, Gisella, additional, Frega, Stefano, additional, Dal Maso, Alessandro, additional, Bonanno, Laura, additional, Paronetto, Chiara, additional, Caumo, Francesca, additional, Calabrese, Fiorella, additional, Rea, Federico, additional, Guarneri, Valentina, additional, and Pasello, Giulia, additional

Published
2022
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5. Microscopical Variables and Tumor Inflammatory Microenvironment Do Not Modify Survival or Recurrence in Stage I-IIA Lung Adenocarcinomas.

Author

Dell'Amore, Andrea, Bonis, Alessandro, Melan, Luca, Silvestrin, Stefano, Cannone, Giorgio, Shamshoum, Fares, Zampieri, Alberto, Pezzuto, Federica, Calabrese, Fiorella, Nicotra, Samuele, Schiavon, Marco, Faccioli, Eleonora, Mammana, Marco, Comacchio, Giovanni Maria, Pasello, Giulia, and Rea, Federico

Subjects
ADENOCARCINOMA, LUNG cancer, PROGRAMMED death-ligand 1, LOG-rank test, CANCER relapse, CELL physiology, RETROSPECTIVE studies, TUMOR classification, LYMPHOCYTES, COMPARATIVE studies
Abstract

Simple Summary: According to guidelines, resection remains a gold standard treatment in early-stage NSCLC. Because of the curative potential of surgery in these patients, microscopical and microenvironmental tumor processes in localized (N0) disease have been superseded for a long time and is a new emerging research field. Here, we investigated the influence of pathological variables and tumor immune environment in terms of survival and recurrence in resected adenocarcinomas staged I-IIA. Microscopical predictors and Tumor Immune Microenvironment (TIME) have been studied less in early-stage NSCLC due to the curative intent of resection and the satisfactory survival rate achievable. Despite this, the emerging literature enforces the role of the immune system and microscopical predictors as prognostic variables in NSCLC and in adenocarcinomas (ADCs) as well. Here, we investigated whether cancer-related microscopical variables and TIME influence survival and recurrence in I-IIA ADCs. We retrospectively collected I-IIA ADCs treated (lobectomy or segmentectomy) at the University Hospital (Padova) between 2016 and 2022. We assigned to pathological variables a cumulative pathological score (PS) resulting as the sum of them. TIME was investigated as tumor-infiltrating lymphocytes (TILs < 11% or ≥11%) and PD-L1 considering its expression (<1% or ≥1%). Then, we compared survival and recurrence according to PS, histology, TILs and PD-L1. A total of 358 I-IIA ADCs met the inclusion criteria. The median PS grew from IA1 to IIA, indicating an increasing microscopical cancer activity. Except for the T-SUVmax, any pathological predictor seemed to be different between PD-L1 < 1% and ≥1%. Histology, PS, TILs and PD-L1 were unable to indicate a survival difference according to the Log-rank test (p = 0.37, p = 0.25, p = 0.41 and p = 0.23). Even the recurrence was non-significant (p = 0.90, p = 0.62, p = 0.97, p = 0.74). According to our findings, resection remains the best upfront treatment in I-IIA ADCs. Microscopical cancer activity grows from IA1 to IIA tumors, but it does not affect outcomes. These outcomes are also unmodified by TIME. Probably, microscopical cancer development and immune reaction against cancer are overwhelmed by an adequate R0-N0 resection. [ABSTRACT FROM AUTHOR]

Published
2023
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6. Sarcopenia as a Predictor of Short- and Long-Term Outcomes in Patients Surgically Treated for Malignant Pleural Mesothelioma

Author

Faccioli, Eleonora, primary, Terzi, Stefano, additional, Giraudo, Chiara, additional, Zuin, Andrea, additional, Modugno, Antonella, additional, Labella, Francesco, additional, Zambello, Giovanni, additional, Lorenzoni, Giulia, additional, Schiavon, Marco, additional, Gregori, Dario, additional, Pasello, Giulia, additional, Calabrese, Fiorella, additional, Dell’Amore, Andrea, additional, and Rea, Federico, additional

Published
2022
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7. Vascular Involvement in Thymic Epithelial Tumors: Surgical and Oncological Outcomes

Author

Comacchio, Giovanni M., primary, Dell’Amore, Andrea, additional, Marino, Maria Carlotta, additional, Russo, Michele Dario, additional, Schiavon, Marco, additional, Mammana, Marco, additional, Faccioli, Eleonora, additional, Lorenzoni, Giulia, additional, Gregori, Dario, additional, Pasello, Giulia, additional, Marulli, Giuseppe, additional, and Rea, Federico, additional

Published
2021
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