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The interpretation of ECGs recorded during clinical drug trials shares many similarities with the clinical interpretation of ECGs, but also differs in several significant ways. The fundamental rules for measurement of ECG intervals and overall ECG interpretation (cardiac rhythm, conduction, etc.) are identical whether an ECG is recorded from a patient having chest pain in an emergency room, or from a healthy subject involved in a clinical drug trial. But, the overall purpose of the evaluation of two such ECGs differs greatly. [ABSTRACT FROM AUTHOR]