1. Medium-Term Survival of Diffuse Coronary Artery Disease Patients following Coronary Artery Reconstruction with the Internal Thoracic Artery
- Author
-
Eric Bezon, Jean-Christophe Cornily, Jean A. Barra, Ahmed Aziz Khalifa, Jean-Noël Choplain, Charles Henri David, Grégoire Le Gal, Service de Chirurgice Cardiaque, Thoracique et Vasculaire (CHRU - CCTV), Centre Hospitalier Régional Universitaire de Brest (CHRU Brest), Département de Cardiologie (CHRU - Cardio), Centre d'Investigation Clinique (CIC - Brest), Université de Brest (UBO)-Institut National de la Santé et de la Recherche Médicale (INSERM), Optimisation des régulations physiologiques (ORPHY (EA 4324)), Institut Brestois Santé Agro Matière (IBSAM), and Université de Brest (UBO)-Université de Brest (UBO)-Université de Brest (UBO)-Centre Hospitalier Régional Universitaire de Brest (CHRU Brest)
- Subjects
Male ,MESH: Exercise Tolerance ,Bypass grafting ,Coronary Artery Disease ,030204 cardiovascular system & hematology ,Coronary artery disease ,Postoperative Complications ,0302 clinical medicine ,MESH: Risk Factors ,Risk Factors ,MESH: Postoperative Complications ,Pharmacology (medical) ,MESH: Coronary Artery Disease ,Hospital Mortality ,030212 general & internal medicine ,Myocardial infarction ,Coronary Artery Bypass ,MESH: Treatment Outcome ,MESH: Aged ,MESH: Middle Aged ,Exercise Tolerance ,Middle Aged ,3. Good health ,Treatment Outcome ,surgical procedures, operative ,medicine.anatomical_structure ,MESH: Survival Analysis ,Cardiology ,Female ,Cardiology and Cardiovascular Medicine ,Artery ,medicine.medical_specialty ,MESH: Mammary Arteries ,Internal thoracic artery ,Medium term ,03 medical and health sciences ,medicine.artery ,Internal medicine ,medicine ,Humans ,MESH: Hospital Mortality ,Mammary Arteries ,Survival analysis ,Aged ,MESH: Humans ,business.industry ,MESH: Coronary Artery Bypass ,Coronary artery reconstruction ,medicine.disease ,Survival Analysis ,MESH: Male ,business ,MESH: Female ,[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology - Abstract
Objective: Diffuse coronary artery disease makes cardiac surgeons hesitant regarding whether coronary artery bypass grafting (CABG) surgery is feasible or not. Coronary artery reconstruction using the internal thoracic artery (ITA) allows bypassing of coronary arteries with diffuse atheromatous plaques without systematically resorting to endarterectomy. The aim of the present study was to evaluate the medium-term results of coronary artery reconstruction. Methods: All patients undergoing coronary artery reconstruction using the ITA between 1999 and 2002 (233 patients) were included in the study. The mean age was 61.9 ± 9.8 years. Two hundred and eighty-one coronary artery reconstructions using the ITA were performed (mean length 3.6 ± 2 cm) for 514 CABGs. Coronary artery reconstruction using the ITA was associated with endarterectomy in 48 cases (17%). Results: In-hospital mortality was 2.6%. Follow-up data were compiled in December 2008. Mean follow-up was 73.4 ± 16.7 months. The actuarial survival rate at 7 years was 89.3 ± 2.1%, and 88% of patients were free of major cardiac events at 7 years. Conclusions: Coronary artery reconstruction gives comparable medium-term results to conventional coronary surgery, even though it is indicated for patients with more severe lesions.
- Published
- 2011