1. Liver hypertrophy after percutaneous portal vein embolization: comparison of N-butyl-2-cyanocrylate versus sodium acrylate-vinyl alcohol copolymer particles in a swine model
- Author
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Efthimia Alexopoulou, Elias Brountzos, Nikolaos Kelekis, Stamatis Theocharis, Georgia Tsoumakidou, Nikolaos Ptohis, and George Mantziaras
- Subjects
Male ,medicine.medical_specialty ,Percutaneous ,Sodium ,medicine.medical_treatment ,Sus scrofa ,Acrylic Resins ,chemistry.chemical_element ,Alcohol ,Muscle hypertrophy ,chemistry.chemical_compound ,medicine ,Animals ,Radiology, Nuclear Medicine and imaging ,Embolization ,medicine.diagnostic_test ,business.industry ,Portal Vein ,Angiography, Digital Subtraction ,Hypertrophy ,Enbucrilate ,Embolization, Therapeutic ,Microspheres ,Surgery ,chemistry ,Liver ,Portal vein embolization ,Angiography ,Polyvinyls ,Tissue Adhesives ,Cardiology and Cardiovascular Medicine ,Liver function tests ,Nuclear medicine ,business ,Tomography, X-Ray Computed - Abstract
Percutaneous portal vein embolization (PPVE) induces hypertrophy of the future liver remnant before hepatic resection. The ideal embolic material has not yet been determined. We compared N-butyl-2-cyanocrylate (NBCA) with sodium acrylate–vinyl alcohol copolymer particles using a swine model. Twelve pigs underwent PPVE. Six pigs (group A) were embolized with NBCA, and 6 pigs (group B) were embolized with sodium acrylate–vinyl alcohol copolymer particles. Computed tomographic volumetry of the embolized lobe (EL) and the nonembolized lobe (NEL), along with liver function tests, was performed before and at 14 and 28 days after embolization. Tissue samples from both lobes were taken 14 and 28 days after PPVE. NEL-volume and NEL-ratio increases were significantly higher in group A at 14 and 28 days after PPVE (78 and 52% and 91 and 66%, respectively) than in group B (32 and 12% and 28 and 10%, respectively) (p
- Published
- 2010