1. Successful Preoperative Chemoembolization in the Treatment of a Giant Malignant Phyllodes Tumor
- Author
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Yasunori Arai, Koichiro Tsugawa, Yasuyuki Kojima, Kazuki Hashimoto, Yasuo Nakajima, Masatomo Doi, and Hidefumi Mimura
- Subjects
Adult ,medicine.medical_specialty ,Embosphere Microspheres ,medicine.medical_treatment ,Breast Neoplasms ,Malignant phyllodes tumor ,Multimodal Imaging ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Phyllodes Tumor ,medicine ,Humans ,Neoplasm ,Radiology, Nuclear Medicine and imaging ,Embolization ,Chemoembolization, Therapeutic ,Mastectomy ,Epirubicin ,medicine.diagnostic_test ,business.industry ,Distant metastasis ,Interventional radiology ,medicine.disease ,Combined Modality Therapy ,Embolization, Therapeutic ,Neoadjuvant Therapy ,Surgery ,030220 oncology & carcinogenesis ,Skin grafting ,Female ,Neoplasm Recurrence, Local ,Cardiology and Cardiovascular Medicine ,business ,medicine.drug - Abstract
The malignant phyllodes tumor is a relatively rare neoplasm and has not previously been a therapeutic target of interventional radiology. Herein, we report a successful case of preoperative chemoembolization of a giant malignant phyllodes tumor. The objective was to achieve sufficient tumor shrinkage before surgery to avoid the requirement for skin grafting after resection. Intra-arterial epirubicin infusion and subsequent embolization with Embosphere Microspheres (BioSphere Medical, Rockland, MA, USA) was undertaken three times over the course of 6 weeks and was well tolerated. The patient underwent surgery without skin grafting. Neither local recurrence nor distant metastasis was observed at 6 months after surgery.
- Published
- 2016
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