1. Pathological changes secondary to pacing leads within the coronary veins.
- Author
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Coelho-Lima J, Chapman J, Lim HS, and Neil DAH
- Subjects
- Equipment Design, Fibrosis, Foreign-Body Reaction etiology, Humans, Inflammation etiology, Coronary Vessels pathology, Foreign-Body Reaction pathology, Inflammation pathology, Pacemaker, Artificial adverse effects
- Abstract
Changes within the Coronary veins secondary to pacing leads have not been described, this study assessed these changes in explanted hearts. Macroscopically fibrous sheaths formed around longstanding leads, leading to slit like channels for venous return in smaller veins. Histologically changes included bland fibrosis, a foreign body response to the lead, a chronic inflammatory response and inflammatory destruction of the media. Individuals responded in different ways with no clear relationship of changes to duration of the lead., (Copyright © 2020 Elsevier Inc. All rights reserved.)
- Published
- 2020
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