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The occurrence of psoriasis vulgaris could be associated with higher psychiatric morbidity. In this case report, we present a patient with bipolar mood disorder and psychotic features whose dermatological signs recovered after the psychiatric disorder partial treatment. Dermatological diseases could be associated with psychiatric disorders, and recurrence of psychiatric symptoms might be associated with the recurrence of the skin lesions.

Heterogeneous findings have been reported regarding the effects of anti-depressive drugs over platelet counts. Among antidepressant drugs, Selective Serotonin Reuptake Inhibitors (SSRIs) has been shown to reduce platelet aggregation. We report a patient with reduction in her platelets counts as well as bruising occurrence following three days of receiving sertraline. In patients with a history of bleeding, ITP or familial ITP, their psychiatric treatment and prescribing SSRI should be done with caution.