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1. Perioperative Management of Type 2N Von Willebrand's Disease with Recombinant Factor VIII in a Patient Undergoing Knee-Replacement Surgery.

Author

Dukka, Srivasavi and Allsup, David John

Subjects
*VON Willebrand disease treatment, *BLOOD coagulation factor VIII, *TOTAL knee replacement, *PERIOPERATIVE care, *HEMORRHAGE, *RARE diseases, *DISEASE susceptibility
Abstract

Type 2NVonWillebrand's disease (2NVWD)is a rare, recessively inherited bleeding disorder, comprising 1-2% of allVWDpatients, usuallymanifesting as amild bleeding diathesis. Treatment includes desmopressin (DDAVP) or intermediate purity plasma-derived FVIII concentrates containing residual VWF. We present a case of a 75-year-old gentleman, incidentally diagnosed with type 2N VWD in 2002 on routine blood testing before surgery with an ISTH bleeding score of 1-2, who was treated with recombinant FVIII preoperatively. [ABSTRACT FROM AUTHOR]

Published
2013
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