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• Hydrogeomorphic processes drive wetland-catchment connectivity dynamics. • Climatic and anthropogenic features influence landscape connectivity patterns. • The upper catchment region is well-connected and contributes to high runoff and erosion. • Identifying hotspots of catchment connectivity change can inform management. Wetlands in semiarid regions are important systems that provide numerous ecosystem services in otherwise dry environments. Their functioning depends on the connected transfer of materials from source to sink which is determined by the degree of landscape connectivity. A combination of catchment characteristics, climatic variables and human activities are important factors driving landscape connectivity; however, wetland management rarely considers all these factors when conserving these systems. In this paper, we evaluate the landscape connectivity of the Mara River catchment in East Africa to understand the hydrogeomorphic processes driving material transfer to the floodplain wetlands. This semiarid catchment hosts the UNESCO World Heritage Serengeti-Mara ecosystem providing a unique opportunity to assess the influence of protected areas on wetland-catchment connectivity patterns. We use the index of connectivity and Emerging Hot Spot analysis to assess the hillslope-channel connectivity and identify specific subcatchments which have contributed positively to the wetland's connectivity over time. The catchment-scale analysis highlights significant spatiotemporal variability in connectivity patterns and associated sediment dynamics. The results reflect that the Upper catchment is highly connected owing to the steep slopes and high rainfall and is likely responsible for the greatest sediment inputs into the fluvial network. Under greater future climatic and anthropogenic pressures, this region is expected to contribute increased sediment inputs into the river which will likely affect the geomorphic response of the downstream floodplain wetlands and may need to be prioritised for management. The protected areas are generally poorly connected due to intact vegetation and their local sediment contribution to the fluvial network is comparatively lower. Consideration of their placement in the catchment is important for managing these ecologically significant areas. Understanding the patterns and variability of hillslope-channel connectivity and the broader-scale landscape connections can help to identify and prioritise existing and emerging hotspots of change in large, semiarid catchments. [ABSTRACT FROM AUTHOR]