1. Transcatheter aortic valve replacement with Evolut R versus Sapien 3 in Japanese patients with a small aortic annulus: The OCEAN-TAVI registry
- Author
-
Kentaro Hayashida, Keiichi Fukuda, Masahiro Yamawaki, Ocean-Tavi Investigators, Yusuke Watanabe, Masanori Yamamoto, Hideyuki Shimizu, Hiroshi Ueno, Toru Naganuma, Hiromu Hase, Futoshi Yamanaka, Nobuhiro Yoshijima, Kensuke Takagi, Ryo Yanagisawa, Minoru Tabata, Makoto Tanaka, Hikaru Tsuruta, Shinichi Shirai, Norio Tada, and Kazuki Mizutani
- Subjects
medicine.medical_specialty ,medicine.medical_treatment ,Hemodynamics ,Regurgitation (circulation) ,030204 cardiovascular system & hematology ,Prosthesis Design ,Transcatheter Aortic Valve Replacement ,03 medical and health sciences ,0302 clinical medicine ,Valve replacement ,Japan ,Interquartile range ,Internal medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,030212 general & internal medicine ,Cardiac skeleton ,Registries ,Body surface area ,business.industry ,General Medicine ,Aortic Valve Stenosis ,Treatment Outcome ,Aortic Valve ,Heart Valve Prosthesis ,Cohort ,Propensity score matching ,Cardiology ,Cardiology and Cardiovascular Medicine ,business - Abstract
OBJECTIVES To compare safety, efficacy, and hemodynamics of transfemoral transcatheter aortic valve replacement (TAVR) using self-expanding and balloon-expandable transcatheter heart valves (THVs) in patients with a small aortic annulus. BACKGROUND Few studies have directly compared TAVR outcomes using third-generation THVs, focusing on patients with small aortic annuli. METHODS In a multicenter TAVR registry, we analyzed data from 576 patients with a small annulus and who underwent transfemoral TAVR using third-generation THVs. Propensity score matching was used to adjust baseline clinical characteristics. RESULTS The device success rate in the overall cohort was 92.0% (Evolut R: 92.1% vs. Sapien 3:92.0%, p = 0.96). One year after TAVR, patients treated with Evolut R maintained a lower mean pressure gradient (mPG) and a higher indexed effective orifice area (iEOA) in the matched cohort {mPG: 9.0 [interquartile range (IQR): 6.0-11.9] vs. 12.0 [IQR: 9.9-16.3] mmHg, p
- Published
- 2020