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1. Viral evolution revealed by bacteriophage PRD1 and human adenovirus coat protein structures

Author

Benson, Stacy D., Bamford Jaana K.H., Bamford, Dennis H., and Burnett, Roger M.

Subjects
Viruses -- Evolution, Bacteriophages -- Genetic aspects, Adenoviruses, Human -- Research, Evolution -- Genetic aspects, Biological sciences
Abstract

Viral evolution as revealed by human adenovirus coat protein structures and bacteriophage PRD1 is discussed. The unusual PRD1 has a membrane beneath the outer icosahedral protein coat. Each of three interlocking subunits in the major coat protein has two 8-stranded viral jelly rolls that are normal for the viral capsid. The P3 molecule, which is the major coat protein, is much like hexon, the equivalent in human adenovirus. The striking similarities strongly suggest evolutionary relationship.

Published
1999

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