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Your search keyword '"Lieber, Michael R."' showing total 10 results
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10 results on '"Lieber, Michael R."'

2. Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

Author

Ma, Yunmei, Pannicke, Ulrich, Schwarz, Klaus, and Lieber, Michael R.

Subjects
Cell research -- Analysis, DNA -- Genetic aspects, Protein kinases -- Genetic aspects, Proteins -- Genetic aspects, Phosphorylation -- Genetic aspects, Gene mutations -- Physiological aspects, Biological sciences
Abstract

Research has been conducted on Artemis protein mutations in humans. Results indicate that DNA-dependent protein kinase and Artemis protein form a physical complex in which this protein kinase phosphorylates Artemis protein.

Published
2002

3. Bidirectional gene organization: a common architectural feature of the human genome

Author

Adachi, Noritaka and Lieber, Michael R.

Subjects
Cell research -- Analysis, Genomes -- Physiological aspects, Genetic regulation -- Physiological aspects, Biological sciences
Abstract

The authors of this letter to editor discuss human genome sequence. The topics of interest include new gene identification and their functions.

Published
2002

10. Hairpin Opening and Overhang Processing by an Artemis/DNA-Dependent Protein Kinase Complex in Nonhomologous End Joining and V(D)J Recombination.

Author

Yunmei Ma, Pannicke, Ulrich, Schwarz, Klaus, and Lieber, Michael R.

Subjects
*PROTEINS, *PROTEIN kinases
Abstract

Examines the formation of a complex by Artemis protein with the 469kDa DNA-dependent protein kinase in the absence of protein. Structure of the protein; Acquisition of endonuclease activity by the protein; Impact of protein mutation on humans.

Published
2002
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